| SP | Siebert, S.Siebert, Sonny † | Indians | R | 166.0 | 28 | 28 | 20 | 4 | 2.46 | .270 | 1.08 | 6.0 | 3.8 | 6.4 | 201.0 | 134 | 55 | 55 | 16 | 84 | 143 | 5 | 0 | 0 | 2 | 23 | 5 | 7 | 3.94 |
| SP | Kluber, C.Kluber, Corey † | Indians | R | 159.0 | 28 | 28 | 20 | 5 | 2.92 | .270 | 1.06 | 6.6 | 3.0 | 10.2 | 200.1 | 146 | 65 | 65 | 13 | 66 | 226 | 4 | 0 | 0 | 1 | 21 | 10 | 4 | 2.73 |
| SP | Hernandez, F.Hernandez, Felix † | SEA | R | 141.0 | 28 | 28 | 17 | 6 | 2.92 | .273 | 1.08 | 7.2 | 2.5 | 9.2 | 203.2 | 162 | 67 | 66 | 23 | 57 | 207 | 3 | 0 | 0 | 2 | 22 | 10 | 5 | 3.42 |
| CL | Sutter, B.Sutter, Bruce † | STL | R | 124.0 | 67 | 0 | 11 | 5 | 4.48 | .300 | 1.29 | 7.9 | 3.8 | 6.5 | 72.1 | 63 | 37 | 36 | 13 | 30 | 52 | 0 | 32 | 9 | 0 | 0 | 0 | 2 | 5.15 |
| SP | Iwakuma, H.Iwakuma, Hisashi | SEA | R | 123.0 | 27 | 27 | 16 | 5 | 3.15 | .291 | 1.21 | 8.9 | 2.0 | 6.8 | 194.0 | 192 | 73 | 68 | 25 | 43 | 146 | 2 | 0 | 0 | 0 | 17 | 4 | 1 | 3.90 |
| SP | Miller, B.Miller, Bryce # | SEA | R | 111.0 | 28 | 28 | 15 | 4 | 3.53 | .266 | 1.03 | 7.1 | 2.2 | 7.3 | 183.2 | 145 | 73 | 72 | 22 | 45 | 148 | 2 | 0 | 0 | 1 | 18 | 10 | 2 | 3.85 |
| SP | Glasnow, T.Glasnow, Tyler † | Dodgers | R | 110.0 | 28 | 28 | 15 | 7 | 3.35 | .291 | 1.22 | 7.7 | 3.3 | 9.3 | 177.1 | 151 | 68 | 66 | 20 | 65 | 183 | 1 | 0 | 0 | 1 | 18 | 2 | 11 | 3.54 |