| SP | Richard, J.Richard, J.R. † | Astros | R | 88.0 | 16 | 16 | 10 | 1 | 2.84 | .247 | 0.96 | 5.8 | 2.8 | 9.6 | 114.0 | 73 | 39 | 36 | 4 | 36 | 121 | 2 | 0 | 0 | 1 | 11 | 3 | 2 | 2.36 |
| SP | Glasnow, T.Glasnow, Tyler † | Defensive Minds | R | 85.0 | 17 | 17 | 11 | 2 | 2.72 | .309 | 1.34 | 8.3 | 3.7 | 8.6 | 106.0 | 98 | 42 | 32 | 7 | 44 | 101 | 0 | 0 | 0 | 0 | 10 | 0 | 8 | 3.20 |
| SP | Arrieta, J.Arrieta, Jake † | Cubbies | R | 83.0 | 17 | 17 | 10 | 4 | 3.08 | .270 | 1.10 | 7.5 | 2.5 | 8.4 | 117.0 | 97 | 41 | 40 | 14 | 32 | 109 | 4 | 0 | 0 | 3 | 13 | 1 | 0 | 3.54 |
| SP | Verlander, J.Verlander, Justin † | Astros | R | 79.0 | 17 | 17 | 10 | 6 | 2.49 | .233 | 0.90 | 6.1 | 2.0 | 7.1 | 119.1 | 81 | 36 | 33 | 11 | 26 | 94 | 1 | 0 | 0 | 0 | 13 | 2 | 2 | 3.33 |
| SP | Bender, C.Bender, Chief # | A's | R | 79.0 | 18 | 18 | 9 | 7 | 2.87 | .235 | 0.92 | 6.8 | 1.5 | 4.5 | 141.0 | 106 | 45 | 45 | 7 | 24 | 70 | 7 | 0 | 0 | 3 | 12 | 0 | 3 | 3.16 |
| SP | Johnson, R.Johnson, Randy | Diamondbacks | L | 74.0 | 17 | 17 | 11 | 4 | 3.99 | .304 | 1.30 | 8.5 | 3.3 | 8.3 | 119.2 | 113 | 53 | 53 | 11 | 43 | 110 | 3 | 0 | 0 | 2 | 9 | 1 | 4 | 3.46 |