| SP | Glasnow, T.Glasnow, Tyler † | Defensive Minds | R | 85.0 | 17 | 17 | 11 | 2 | 2.72 | .309 | 1.34 | 8.3 | 3.7 | 8.6 | 106.0 | 98 | 42 | 32 | 7 | 44 | 101 | 0 | 0 | 0 | 0 | 10 | 0 | 8 | 3.20 |
| SP | Richard, J.Richard, J.R. † | Astros | R | 85.0 | 17 | 17 | 10 | 1 | 3.09 | .254 | 1.00 | 6.0 | 3.0 | 9.5 | 116.1 | 77 | 43 | 40 | 5 | 39 | 122 | 2 | 0 | 0 | 1 | 11 | 3 | 2 | 2.54 |
| SP | Arrieta, J.Arrieta, Jake † | Cubbies | R | 83.0 | 17 | 17 | 10 | 4 | 3.08 | .270 | 1.10 | 7.5 | 2.5 | 8.4 | 117.0 | 97 | 41 | 40 | 14 | 32 | 109 | 4 | 0 | 0 | 3 | 13 | 1 | 0 | 3.54 |
| SP | Verlander, J.Verlander, Justin † | Astros | R | 79.0 | 17 | 17 | 10 | 6 | 2.49 | .233 | 0.90 | 6.1 | 2.0 | 7.1 | 119.1 | 81 | 36 | 33 | 11 | 26 | 94 | 1 | 0 | 0 | 0 | 13 | 2 | 2 | 3.33 |
| SP | Bender, C.Bender, Chief # | A's | R | 79.0 | 18 | 18 | 9 | 7 | 2.87 | .235 | 0.92 | 6.8 | 1.5 | 4.5 | 141.0 | 106 | 45 | 45 | 7 | 24 | 70 | 7 | 0 | 0 | 3 | 12 | 0 | 3 | 3.16 |
| CL | Eckersley, D.Eckersley, Dennis † | A's | R | 77.5 | 33 | 0 | 3 | 2 | 2.57 | .239 | 0.91 | 6.7 | 1.5 | 7.5 | 35.0 | 26 | 10 | 10 | 2 | 6 | 29 | 0 | 23 | 2 | 0 | 0 | 1 | 0 | 2.69 |