| SP | Mathewson, C.Mathewson, Christy † $ | Warriors | R | 125.0 | 23 | 23 | 15 | 4 | 2.83 | .267 | 1.07 | 8.1 | 1.5 | 4.4 | 181.1 | 163 | 65 | 57 | 20 | 31 | 89 | 5 | 0 | 0 | 3 | 18 | 4 | 0 | 4.03 |
| SP | deGrom, J.deGrom, Jacob † $$ | Cubbies | R | 121.0 | 24 | 24 | 14 | 5 | 2.93 | .270 | 1.10 | 7.3 | 2.6 | 9.0 | 184.1 | 149 | 66 | 60 | 11 | 53 | 185 | 4 | 0 | 0 | 0 | 18 | 3 | 0 | 2.68 |
| SP | Arrieta, J.Arrieta, Jake # | Classics | R | 120.0 | 25 | 25 | 14 | 8 | 2.86 | .256 | 1.00 | 6.6 | 2.5 | 9.5 | 182.1 | 133 | 60 | 58 | 19 | 50 | 192 | 5 | 0 | 0 | 2 | 21 | 5 | 1 | 3.15 |
| SP | Johnson, W.Johnson, Walter $ | Ducks | R | 112.0 | 25 | 25 | 14 | 6 | 3.09 | .256 | 1.02 | 7.3 | 1.9 | 5.1 | 177.2 | 144 | 65 | 61 | 16 | 38 | 101 | 7 | 0 | 0 | 2 | 17 | 1 | 2 | 3.69 |
| SP | Martinez, P.Martinez, Pedro † | INFIDELS | R | 105.0 | 25 | 25 | 15 | 5 | 3.63 | .269 | 1.09 | 7.3 | 2.5 | 9.0 | 161.0 | 131 | 73 | 65 | 21 | 45 | 161 | 2 | 0 | 0 | 1 | 15 | 2 | 1 | 3.57 |
| CL | Doolittle, S.Doolittle, Sean † | Ducks | L | 88.0 | 48 | 0 | 2 | 4 | 3.10 | .225 | 0.85 | 5.7 | 2.0 | 9.6 | 49.1 | 31 | 17 | 17 | 6 | 11 | 52 | 0 | 30 | 3 | 0 | 0 | 1 | 0 | 3.20 |