| SP | Gibson, B.Gibson, Bob † # | Redbirds | R | 191.0 | 36 | 36 | 24 | 11 | 3.14 | .270 | 1.10 | 7.5 | 2.4 | 4.6 | 297.2 | 247 | 115 | 104 | 15 | 80 | 152 | 19 | 0 | 0 | 1 | 23 | 4 | 5 | 3.48 |
| SP | Chamberlain, E.Chamberlain, Elton † | Redbirds | R | 184.0 | 35 | 35 | 20 | 9 | 2.92 | .277 | 1.14 | 6.9 | 3.3 | 4.2 | 296.1 | 228 | 104 | 96 | 20 | 109 | 139 | 19 | 0 | 0 | 4 | 25 | 4 | 0 | 4.08 |
| SP | Titcomb, C.Titcomb, Cannonball † | Sluggers | L | 179.0 | 34 | 34 | 22 | 6 | 2.99 | .285 | 1.19 | 7.9 | 2.8 | 4.0 | 262.0 | 231 | 95 | 87 | 19 | 81 | 115 | 12 | 0 | 0 | 2 | 24 | 2 | 13 | 4.02 |
| CL | deGrom, J.deGrom, Jacob † | Cobras | R | 177.0 | 72 | 0 | 10 | 5 | 1.79 | .218 | 0.82 | 5.8 | 1.6 | 8.6 | 100.1 | 64 | 21 | 20 | 5 | 18 | 96 | 0 | 40 | 6 | 0 | 0 | 2 | 0 | 2.33 |
| SP | Skubal, T.Skubal, Tarik # | Admirals | L | 147.0 | 34 | 34 | 19 | 6 | 3.07 | .276 | 1.13 | 8.4 | 1.8 | 8.6 | 220.0 | 206 | 79 | 75 | 18 | 43 | 210 | 0 | 0 | 0 | 0 | 25 | 2 | 2 | 2.77 |
| CL | Greene, S.Greene, Shane † | Admirals | R | 139.5 | 71 | 0 | 3 | 6 | 2.71 | .263 | 1.07 | 5.8 | 3.8 | 8.4 | 73.0 | 47 | 25 | 22 | 6 | 31 | 68 | 0 | 47 | 4 | 0 | 0 | 0 | 0 | 3.48 |