| SP | Richard, J.Richard, J.R. † | Tigres | R | 143.0 | 32 | 32 | 17 | 8 | 3.00 | .266 | 1.07 | 6.4 | 3.3 | 7.1 | 228.1 | 161 | 77 | 76 | 15 | 83 | 179 | 7 | 0 | 0 | 3 | 23 | 4 | 4 | 3.43 |
| SP | Fernandez, J.Fernandez, Jose | Tigres | R | 125.0 | 31 | 31 | 17 | 8 | 3.26 | .279 | 1.14 | 6.8 | 3.5 | 7.4 | 210.0 | 158 | 77 | 76 | 15 | 81 | 172 | 1 | 0 | 0 | 1 | 22 | 5 | 4 | 3.52 |
| SP | Cicotte, E.Cicotte, Eddie # | Nightmares | R | 121.0 | 31 | 31 | 19 | 9 | 3.90 | .293 | 1.21 | 8.3 | 2.6 | 5.1 | 228.1 | 210 | 116 | 99 | 20 | 66 | 130 | 6 | 0 | 0 | 1 | 19 | 8 | 2 | 3.97 |
| SP | McDowell, S.McDowell, Sam † # | Corn Shuckers | L | 120.0 | 32 | 30 | 16 | 6 | 3.25 | .305 | 1.31 | 7.4 | 4.4 | 7.9 | 191.1 | 156 | 74 | 69 | 11 | 94 | 168 | 1 | 0 | 0 | 0 | 18 | 2 | 12 | 3.50 |
| SP | Koufax, S.Koufax, Sandy # | Tigers | L | 116.0 | 33 | 33 | 14 | 16 | 3.45 | .269 | 1.09 | 7.6 | 2.2 | 8.2 | 247.2 | 208 | 100 | 95 | 24 | 61 | 226 | 15 | 0 | 0 | 3 | 20 | 4 | 8 | 3.22 |
| SP | McLain, D.McLain, Denny # | Ball Breakers | R | 114.0 | 31 | 31 | 18 | 11 | 4.32 | .289 | 1.20 | 8.9 | 2.0 | 5.8 | 229.1 | 226 | 117 | 110 | 27 | 50 | 147 | 14 | 0 | 0 | 3 | 15 | 3 | 5 | 3.94 |