| SP | Pfiester, J.Pfiester, Jack † # | Green Frogs | L | 121.0 | 25 | 24 | 15 | 7 | 3.14 | .283 | 1.17 | 8.2 | 2.4 | 4.2 | 180.2 | 164 | 70 | 63 | 13 | 47 | 84 | 12 | 0 | 0 | 4 | 15 | 3 | 5 | 3.84 |
| SP | Richard, J.Richard, J.R. † | Tigres | R | 119.0 | 25 | 25 | 16 | 6 | 3.01 | .284 | 1.18 | 7.0 | 3.7 | 6.4 | 170.2 | 132 | 61 | 57 | 11 | 69 | 121 | 2 | 0 | 0 | 2 | 19 | 2 | 6 | 3.67 |
| RP | Chapman, A.Chapman, Aroldis † | Tigres | L | 112.0 | 62 | 0 | 10 | 0 | 1.72 | .232 | 0.91 | 4.1 | 4.1 | 9.8 | 83.2 | 38 | 20 | 16 | 3 | 38 | 90 | 0 | 10 | 0 | 0 | 0 | 0 | 3 | 2.67 |
| CL | Kimbrel, C.Kimbrel, Craig † | Corn Shuckers | R | 96.5 | 56 | 0 | 4 | 5 | 3.21 | .236 | 0.89 | 5.6 | 2.5 | 9.3 | 61.2 | 38 | 23 | 22 | 7 | 17 | 63 | 0 | 29 | 2 | 0 | 0 | 2 | 4 | 3.36 |
| SP | Johnson, R.Johnson, Randy # | Tigres | L | 96.0 | 24 | 24 | 13 | 5 | 3.14 | .266 | 1.07 | 7.6 | 2.1 | 7.0 | 154.2 | 130 | 54 | 54 | 17 | 36 | 119 | 1 | 0 | 0 | 0 | 19 | 2 | 2 | 3.63 |
| SP | Kershaw, C.Kershaw, Clayton | Bees | L | 93.0 | 25 | 25 | 11 | 7 | 3.39 | .290 | 1.22 | 8.5 | 2.5 | 8.2 | 185.2 | 175 | 81 | 70 | 21 | 51 | 168 | 5 | 0 | 0 | 1 | 16 | 2 | 5 | 3.52 |