| SP | Peralta, F.Peralta, Freddy † | Pull-up Jimbos | R | 166.0 | 32 | 32 | 20 | 1 | 2.57 | .278 | 1.13 | 6.0 | 4.1 | 9.9 | 189.0 | 127 | 55 | 54 | 12 | 86 | 208 | 0 | 0 | 0 | 0 | 17 | 5 | 5 | 3.07 |
| CL | Chapman, A.Chapman, Aroldis † | Flames | L | 146.5 | 87 | 0 | 9 | 4 | 2.50 | .303 | 1.26 | 6.4 | 4.9 | 10.3 | 101.0 | 72 | 28 | 28 | 6 | 55 | 116 | 0 | 29 | 0 | 0 | 0 | 5 | 8 | 3.26 |
| SP | Imanaga, S.Imanaga, Shota † | Pull-up Jimbos | L | 142.5 | 33 | 32 | 20 | 5 | 3.33 | .282 | 1.14 | 8.1 | 2.1 | 7.9 | 197.1 | 178 | 78 | 73 | 29 | 47 | 174 | 0 | 1 | 0 | 0 | 17 | 7 | 1 | 3.97 |
| SP | Skubal, T.Skubal, Tarik # | Lions | L | 138.0 | 35 | 35 | 15 | 8 | 2.99 | .261 | 1.05 | 7.4 | 2.0 | 10.8 | 241.0 | 199 | 85 | 80 | 21 | 53 | 289 | 2 | 0 | 0 | 0 | 26 | 3 | 3 | 2.43 |
| CL | Svanson, M.Svanson, Matt † | Knights | R | 128.5 | 68 | 0 | 9 | 9 | 2.96 | .303 | 1.29 | 7.0 | 4.6 | 10.7 | 76.0 | 59 | 25 | 25 | 6 | 39 | 90 | 0 | 33 | 5 | 0 | 0 | 1 | 1 | 3.24 |
| SP | Glasnow, T.Glasnow, Tyler † | Pull-up Jimbos | R | 114.0 | 34 | 34 | 16 | 7 | 3.25 | .299 | 1.25 | 6.8 | 4.5 | 9.6 | 174.2 | 131 | 63 | 63 | 17 | 87 | 186 | 0 | 0 | 0 | 0 | 5 | 5 | 4 | 3.72 |