| SP | Eovaldi, N.Eovaldi, Nathan † | Knights | R | 83.0 | 19 | 19 | 11 | 2 | 3.22 | .267 | 1.07 | 7.5 | 2.1 | 8.5 | 117.1 | 98 | 43 | 42 | 10 | 27 | 111 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 2.98 |
| SP | Rogers, T.Rogers, Trevor † | Pull-up Jimbos | L | 74.0 | 18 | 18 | 10 | 3 | 3.22 | .298 | 1.26 | 8.0 | 3.4 | 8.4 | 114.2 | 101 | 41 | 41 | 11 | 43 | 106 | 0 | 0 | 0 | 0 | 12 | 2 | 0 | 3.58 |
| SP | Schwellenbach, S.Schwellenbach, Spencer † | Knights | R | 72.0 | 17 | 17 | 9 | 4 | 3.02 | .266 | 1.05 | 7.1 | 2.4 | 8.0 | 113.1 | 89 | 39 | 38 | 12 | 30 | 100 | 2 | 0 | 0 | 1 | 12 | 4 | 0 | 3.51 |
| SP | Gilbert, L.Gilbert, Logan # | Lions | R | 61.0 | 18 | 18 | 8 | 5 | 3.12 | .293 | 1.22 | 7.7 | 3.3 | 10.5 | 104.0 | 89 | 36 | 36 | 9 | 38 | 121 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 2.95 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu | Q's | R | 61.0 | 18 | 18 | 6 | 3 | 2.81 | .291 | 1.21 | 7.6 | 3.3 | 9.8 | 112.0 | 94 | 35 | 35 | 12 | 41 | 122 | 0 | 0 | 0 | 0 | 13 | 3 | 2 | 3.39 |
| SP | deGrom, J.deGrom, Jacob # | Sharks | R | 58.0 | 18 | 18 | 6 | 4 | 2.88 | .257 | 1.01 | 6.7 | 2.4 | 10.3 | 115.2 | 86 | 38 | 37 | 11 | 31 | 131 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 2.85 |
| RP | Rodríguez, R.Rodríguez, Randy † | Mustangs | R | 57.5 | 59 | 0 | 9 | 4 | 4.29 | .321 | 1.36 | 9.2 | 3.1 | 10.1 | 79.2 | 81 | 39 | 38 | 10 | 27 | 89 | 0 | 5 | 4 | 0 | 0 | 5 | 4 | 3.61 |