| SP | Verlander, J.Verlander, Justin # $$ | Night Hawks | R | 155.0 | 36 | 36 | 21 | 10 | 3.38 | .302 | 1.27 | 9.3 | 2.2 | 7.7 | 261.1 | 269 | 103 | 98 | 28 | 63 | 224 | 5 | 0 | 0 | 0 | 24 | 7 | 2 | 3.48 |
| SP | Mathewson, C.Mathewson, Christy | Classics | R | 153.0 | 34 | 34 | 22 | 5 | 3.58 | .287 | 1.17 | 8.5 | 2.1 | 4.6 | 244.0 | 230 | 101 | 97 | 27 | 56 | 125 | 3 | 0 | 0 | 2 | 18 | 8 | 3 | 4.20 |
| SP | Alexander, P.Alexander, Pete † $ | Gaels | R | 151.0 | 33 | 33 | 18 | 8 | 2.57 | .272 | 1.11 | 7.3 | 2.7 | 4.9 | 224.1 | 182 | 77 | 64 | 14 | 68 | 122 | 5 | 0 | 0 | 2 | 24 | 2 | 3 | 3.66 |
| CL | Chapman, A.Chapman, Aroldis † | Classics | L | 148.0 | 68 | 0 | 1 | 1 | 3.54 | .280 | 1.16 | 6.0 | 4.4 | 9.1 | 61.0 | 41 | 25 | 24 | 2 | 30 | 62 | 0 | 56 | 9 | 0 | 0 | 0 | 6 | 2.87 |
| CL | Betances, D.Betances, Dellin † $ | Wawa’s | R | 143.5 | 70 | 0 | 5 | 4 | 2.56 | .304 | 1.29 | 7.3 | 4.4 | 9.0 | 70.1 | 57 | 24 | 20 | 4 | 34 | 70 | 0 | 43 | 4 | 0 | 0 | 1 | 6 | 3.24 |
| SP | Leonard, D.Leonard, Dutch | Gaels | L | 138.0 | 35 | 35 | 18 | 8 | 3.03 | .284 | 1.18 | 7.8 | 2.8 | 5.3 | 235.0 | 204 | 87 | 79 | 14 | 74 | 139 | 2 | 0 | 0 | 0 | 25 | 1 | 4 | 3.55 |
| SP | Koufax, S.Koufax, Sandy # | Spiders | L | 127.0 | 34 | 34 | 15 | 12 | 3.72 | .287 | 1.20 | 8.0 | 2.7 | 8.2 | 254.0 | 227 | 106 | 105 | 24 | 77 | 231 | 17 | 0 | 0 | 4 | 19 | 3 | 2 | 3.35 |