| SP | Kershaw, C.Kershaw, Clayton † | Skull Sword | L | 165.0 | 24 | 24 | 17 | 2 | 2.19 | .264 | 1.05 | 7.6 | 1.8 | 8.8 | 185.1 | 157 | 47 | 45 | 8 | 38 | 180 | 8 | 0 | 0 | 4 | 18 | 4 | 4 | 2.30 |
| CL | Chapman, A.Chapman, Aroldis † | Feens | L | 106.5 | 52 | 0 | 5 | 3 | 2.72 | .297 | 1.21 | 5.3 | 5.7 | 11.6 | 49.2 | 29 | 16 | 15 | 2 | 31 | 63 | 0 | 29 | 2 | 0 | 0 | 3 | 3 | 3.04 |
| SP | Teheran, J.Teheran, Julio † | Tigers | R | 98.0 | 23 | 23 | 14 | 4 | 3.37 | .283 | 1.18 | 8.1 | 2.5 | 7.0 | 147.0 | 132 | 56 | 55 | 10 | 41 | 114 | 1 | 0 | 0 | 0 | 16 | 1 | 1 | 3.19 |
| SP | deGrom, J.deGrom, Jacob # | Oilers | R | 91.0 | 23 | 23 | 11 | 2 | 3.25 | .275 | 1.11 | 7.7 | 2.4 | 9.1 | 149.2 | 127 | 56 | 54 | 10 | 39 | 151 | 0 | 0 | 0 | 0 | 17 | 4 | 1 | 2.71 |
| CL | Betances, D.Betances, Dellin | Oilers | R | 89.5 | 40 | 0 | 5 | 3 | 3.32 | .269 | 1.08 | 7.7 | 2.3 | 11.3 | 40.2 | 34 | 15 | 15 | 0 | 10 | 50 | 0 | 25 | 3 | 0 | 0 | 1 | 0 | 1.33 |
| SP | Hammel, J.Hammel, Jason # | Skull Sword | R | 85.0 | 23 | 23 | 9 | 5 | 2.33 | .237 | 0.90 | 6.5 | 1.6 | 7.2 | 139.1 | 101 | 37 | 36 | 11 | 24 | 111 | 0 | 0 | 0 | 0 | 13 | 5 | 3 | 3.06 |
| SP | Holland, D.Holland, Derek | Panther | L | 77.0 | 23 | 23 | 10 | 8 | 3.08 | .280 | 1.16 | 8.7 | 1.8 | 5.9 | 155.0 | 149 | 54 | 53 | 11 | 31 | 102 | 1 | 0 | 0 | 1 | 15 | 1 | 1 | 3.23 |