| SP | Arrieta, J.Arrieta, Jake † | Elephants | R | 96.0 | 18 | 18 | 11 | 5 | 2.26 | .284 | 1.15 | 6.7 | 3.7 | 9.8 | 123.2 | 92 | 34 | 31 | 12 | 50 | 134 | 2 | 0 | 0 | 1 | 14 | 5 | 3 | 3.43 |
| CL | Eckersley, D.Eckersley, Dennis † | Spartans | R | 86.0 | 36 | 0 | 5 | 2 | 2.45 | .252 | 0.98 | 8.3 | 0.8 | 9.8 | 36.2 | 33 | 10 | 10 | 6 | 3 | 39 | 0 | 22 | 3 | 0 | 0 | 1 | 0 | 3.33 |
| CL | Jansen, K.Jansen, Kenley † | HURRICANES | R | 79.5 | 39 | 0 | 3 | 1 | 3.07 | .250 | 0.95 | 5.5 | 3.1 | 9.0 | 41.0 | 25 | 15 | 14 | 4 | 14 | 41 | 0 | 23 | 2 | 0 | 0 | 2 | 0 | 3.44 |
| SP | Fernandez, J.Fernandez, Jose † | Warriors | R | 78.0 | 19 | 19 | 11 | 3 | 3.57 | .304 | 1.27 | 7.4 | 4.1 | 9.2 | 123.2 | 101 | 49 | 49 | 14 | 56 | 126 | 0 | 0 | 0 | 0 | 14 | 5 | 0 | 3.92 |
| SP | Martinez, P.Martinez, Pedro † | Tigers | R | 74.0 | 19 | 19 | 8 | 5 | 2.87 | .258 | 1.02 | 7.0 | 2.2 | 9.1 | 135.0 | 105 | 43 | 43 | 12 | 33 | 136 | 1 | 0 | 0 | 0 | 15 | 3 | 2 | 2.94 |
| SP | Richard, J.Richard, J.R. $ | Charlie Browns | R | 73.0 | 19 | 19 | 9 | 7 | 2.78 | .293 | 1.21 | 6.2 | 4.7 | 9.6 | 129.1 | 89 | 44 | 40 | 7 | 68 | 138 | 0 | 0 | 0 | 0 | 14 | 4 | 2 | 3.24 |
| SP | deGrom, J.deGrom, Jacob # $ | Eagles | R | 71.0 | 19 | 19 | 9 | 6 | 3.32 | .274 | 1.07 | 7.0 | 2.8 | 10.5 | 124.2 | 96 | 46 | 46 | 7 | 38 | 145 | 2 | 0 | 0 | 2 | 15 | 7 | 0 | 2.48 |
| SP | Scherzer, M.Scherzer, Max † # | Demons | R | 71.0 | 19 | 19 | 7 | 6 | 2.68 | .273 | 1.12 | 7.7 | 2.4 | 10.3 | 134.1 | 115 | 46 | 40 | 10 | 35 | 153 | 2 | 0 | 0 | 0 | 14 | 1 | 0 | 2.49 |