| SP | Guidry, R.Guidry, Ron † # | Stars | L | 118.0 | 20 | 20 | 13 | 3 | 2.18 | .243 | 0.94 | 6.3 | 2.2 | 5.8 | 148.2 | 104 | 38 | 36 | 8 | 36 | 96 | 4 | 0 | 0 | 1 | 16 | 3 | 3 | 3.20 |
| SP | deGrom, J.deGrom, Jacob † | PECKERHEADS | R | 95.0 | 22 | 22 | 11 | 5 | 2.60 | .276 | 1.11 | 7.3 | 2.7 | 8.9 | 145.1 | 118 | 45 | 42 | 13 | 43 | 144 | 0 | 0 | 0 | 0 | 15 | 5 | 0 | 3.17 |
| SP | Lundgren, C.Lundgren, Carl † | Redshirts | R | 91.0 | 20 | 20 | 13 | 3 | 3.41 | .297 | 1.25 | 6.3 | 4.9 | 4.2 | 142.1 | 100 | 56 | 54 | 11 | 78 | 66 | 3 | 0 | 0 | 0 | 13 | 2 | 3 | 4.77 |
| SP | Santana, J.Santana, Johan | Red Bears | L | 90.0 | 21 | 21 | 10 | 3 | 3.33 | .264 | 1.06 | 7.2 | 2.4 | 9.4 | 154.0 | 123 | 61 | 57 | 22 | 41 | 161 | 4 | 0 | 0 | 1 | 14 | 2 | 1 | 3.60 |
| CL | Miller, A.Miller, Andrew † | Redshirts | L | 86.5 | 46 | 0 | 3 | 3 | 2.74 | .242 | 0.93 | 5.5 | 2.9 | 9.0 | 46.0 | 28 | 14 | 14 | 4 | 15 | 46 | 0 | 27 | 4 | 0 | 0 | 1 | 0 | 3.17 |
| CL | Kimbrel, C.Kimbrel, Craig † $ | Sharks | R | 81.0 | 49 | 0 | 2 | 1 | 1.93 | .273 | 1.11 | 6.3 | 3.7 | 10.3 | 56.0 | 39 | 12 | 12 | 3 | 23 | 64 | 0 | 20 | 1 | 0 | 0 | 1 | 1 | 2.70 |
| SP | McNally, D.McNally, Dave # | Red Bears | L | 78.0 | 22 | 22 | 11 | 9 | 3.79 | .267 | 1.07 | 7.6 | 2.0 | 6.5 | 159.0 | 134 | 70 | 67 | 19 | 36 | 115 | 8 | 0 | 0 | 3 | 14 | 4 | 1 | 3.86 |
| RP | Zimmerman, J.Zimmerman, Jeff † | Reapers | R | 77.0 | 54 | 0 | 8 | 1 | 3.31 | .252 | 1.01 | 5.8 | 3.3 | 4.6 | 73.1 | 47 | 30 | 27 | 10 | 27 | 37 | 0 | 10 | 2 | 0 | 0 | 0 | 1 | 4.88 |