| SP | Dotson, R.Dotson, Richard | Angels | R | 169.0 | 37 | 36 | 20 | 11 | 2.62 | .283 | 1.17 | 7.1 | 3.5 | 5.1 | 260.2 | 205 | 86 | 76 | 17 | 100 | 148 | 7 | 0 | 1 | 5 | 28 | 4 | 3 | 3.91 |
| SP | Messersmith, A.Messersmith, Andy | Astros | R | 168.0 | 33 | 33 | 18 | 10 | 2.70 | .266 | 1.07 | 6.7 | 3.0 | 6.0 | 253.1 | 187 | 82 | 76 | 19 | 84 | 170 | 15 | 0 | 0 | 5 | 24 | 4 | 5 | 3.68 |
| SP | Tanaka, M.Tanaka, Masahiro | Tigers | R | 151.0 | 33 | 33 | 16 | 8 | 2.29 | .262 | 1.06 | 7.5 | 2.1 | 6.0 | 228.1 | 189 | 62 | 58 | 11 | 52 | 152 | 5 | 0 | 0 | 2 | 27 | 2 | 1 | 3.00 |
| SP | Kershaw, C.Kershaw, Clayton | Athletics | L | 150.0 | 35 | 35 | 18 | 9 | 3.16 | .276 | 1.13 | 7.3 | 2.9 | 8.2 | 251.0 | 203 | 95 | 88 | 26 | 80 | 228 | 6 | 0 | 0 | 2 | 24 | 4 | 4 | 3.53 |
| SP | Scherzer, M.Scherzer, Max | Orioles | R | 145.0 | 33 | 33 | 19 | 10 | 3.16 | .299 | 1.26 | 8.0 | 3.3 | 8.5 | 225.1 | 200 | 81 | 79 | 16 | 83 | 213 | 6 | 0 | 0 | 1 | 26 | 5 | 5 | 3.20 |
| SP | Lincecum, T.Lincecum, Tim | Athletics | R | 126.0 | 33 | 33 | 15 | 9 | 3.16 | .290 | 1.21 | 6.9 | 4.0 | 7.6 | 228.0 | 175 | 84 | 80 | 18 | 102 | 192 | 5 | 0 | 0 | 2 | 26 | 3 | 4 | 3.72 |
| RP | Mikkelsen, P.Mikkelsen, Pete | White Sox | R | 114.5 | 83 | 0 | 10 | 5 | 3.03 | .276 | 1.10 | 6.1 | 3.8 | 6.0 | 148.1 | 101 | 56 | 50 | 10 | 62 | 99 | 0 | 15 | 3 | 0 | 0 | 7 | 3 | 3.94 |