| SP | Martinez, P.Martinez, Pedro † | Black Sox | R | 108.0 | 27 | 27 | 13 | 10 | 3.21 | .272 | 1.10 | 7.1 | 2.8 | 8.1 | 199.1 | 157 | 75 | 71 | 19 | 63 | 180 | 7 | 0 | 0 | 2 | 19 | 3 | 0 | 3.43 |
| SP | Koufax, S.Koufax, Sandy † | Darts QD7 | L | 105.0 | 27 | 27 | 15 | 8 | 3.34 | .275 | 1.12 | 7.6 | 2.5 | 7.6 | 183.0 | 155 | 68 | 68 | 19 | 50 | 155 | 1 | 0 | 0 | 0 | 19 | 3 | 1 | 3.52 |
| SP | Alexander, P.Alexander, Pete | Slickers | R | 103.0 | 25 | 25 | 13 | 6 | 3.14 | .271 | 1.09 | 7.2 | 2.7 | 4.7 | 183.2 | 146 | 70 | 64 | 6 | 55 | 95 | 4 | 0 | 0 | 2 | 17 | 4 | 2 | 3.36 |
| CL | Kimbrel, C.Kimbrel, Craig † | Black Sox | R | 101.5 | 52 | 0 | 8 | 3 | 3.29 | .302 | 1.26 | 7.0 | 4.5 | 8.8 | 54.2 | 42 | 20 | 20 | 6 | 27 | 53 | 0 | 23 | 4 | 0 | 0 | 2 | 4 | 4.09 |
| SP | Leonard, D.Leonard, Dutch | Monarchs | L | 98.0 | 27 | 27 | 14 | 5 | 3.35 | .290 | 1.19 | 6.9 | 3.8 | 5.1 | 166.2 | 128 | 64 | 62 | 12 | 70 | 94 | 1 | 0 | 0 | 0 | 19 | 6 | 1 | 4.18 |
| CL | Chapman, A.Chapman, Aroldis † | Monarchs | L | 96.5 | 58 | 0 | 4 | 7 | 3.12 | .293 | 1.23 | 6.5 | 4.6 | 9.0 | 69.1 | 50 | 26 | 24 | 6 | 35 | 69 | 0 | 29 | 1 | 0 | 0 | 1 | 4 | 3.70 |