| SP | Strasburg, S.Strasburg, Stephen † $$ | White Sox | R | 166.0 | 36 | 35 | 21 | 10 | 2.76 | .254 | 1.01 | 6.5 | 2.5 | 9.2 | 237.2 | 172 | 80 | 73 | 25 | 67 | 243 | 2 | 0 | 0 | 1 | 0 | 4 | 3 | 3.22 |
| SP | Scherzer, M.Scherzer, Max † $ | Royals | R | 157.0 | 37 | 37 | 20 | 10 | 3.33 | .277 | 1.14 | 7.2 | 3.1 | 10.8 | 256.2 | 204 | 98 | 95 | 25 | 88 | 308 | 3 | 0 | 0 | 2 | 0 | 3 | 6 | 2.93 |
| SP | Stinnett, J.Stinnett, Jake † $$ | Mariners | R | 157.0 | 38 | 38 | 20 | 11 | 3.56 | .277 | 1.14 | 7.7 | 2.5 | 6.6 | 270.1 | 232 | 111 | 107 | 40 | 75 | 199 | 16 | 0 | 0 | 4 | 0 | 3 | 0 | 4.32 |
| RP | Garcia, Y.Garcia, Yimi $$ | Athletics | R | 145.0 | 113 | 0 | 8 | 6 | 2.22 | .232 | 0.90 | 6.0 | 2.2 | 11.3 | 182.2 | 121 | 48 | 45 | 17 | 44 | 228 | 0 | 18 | 3 | 0 | 0 | 1 | 1 | 2.45 |
| CL | Pearce, M.Pearce, Matt † $$ | Red Sox | R | 139.0 | 94 | 0 | 8 | 9 | 2.75 | .249 | 0.99 | 6.3 | 2.6 | 8.2 | 167.0 | 116 | 52 | 51 | 18 | 49 | 153 | 0 | 26 | 1 | 0 | 0 | 1 | 2 | 3.47 |
| RP | Ravenelle, A.Ravenelle, Adam † $ | Royals | R | 136.0 | 87 | 0 | 8 | 7 | 2.03 | .262 | 1.03 | 6.9 | 2.5 | 8.0 | 168.1 | 128 | 42 | 38 | 14 | 46 | 150 | 0 | 20 | 7 | 0 | 0 | 5 | 6 | 3.21 |
| SP | Ishida, K.Ishida, Kenta + | Orioles | L | 124.0 | 37 | 37 | 16 | 12 | 3.60 | .284 | 1.18 | 8.0 | 2.6 | 7.3 | 255.1 | 226 | 131 | 102 | 36 | 75 | 206 | 12 | 0 | 0 | 0 | 0 | 3 | 5 | 4.14 |