| CL | Jansen, K.Jansen, Kenley † | Mets | R | 100.0 | 50 | 0 | 4 | 2 | 1.99 | .225 | 0.82 | 5.7 | 1.7 | 10.2 | 58.2 | 37 | 13 | 13 | 6 | 11 | 66 | 0 | 24 | 0 | 0 | 0 | 3 | 0 | 2.79 |
| SP | Weaver, J.Weaver, Jered † | Bucs | R | 80.0 | 19 | 19 | 13 | 4 | 3.94 | .313 | 1.35 | 8.9 | 3.3 | 7.1 | 132.1 | 130 | 60 | 58 | 17 | 48 | 104 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 4.26 |
| SP | deGrom, J.deGrom, Jacob # | Dragons | R | 80.0 | 21 | 21 | 11 | 4 | 3.72 | .283 | 1.16 | 8.2 | 2.3 | 10.7 | 135.1 | 123 | 59 | 56 | 13 | 34 | 161 | 1 | 0 | 0 | 0 | 13 | 3 | 3 | 2.69 |
| SP | Flaherty, J.Flaherty, Jack † | Gladiators | R | 77.0 | 21 | 21 | 8 | 6 | 2.57 | .272 | 1.11 | 7.1 | 2.8 | 10.7 | 136.1 | 108 | 43 | 39 | 9 | 43 | 161 | 0 | 0 | 0 | 0 | 15 | 2 | 1 | 2.49 |
| SP | Buehler, W.Buehler, Walker # | Bombers | R | 77.0 | 20 | 12 | 8 | 0 | 2.76 | .278 | 1.13 | 7.1 | 3.0 | 7.9 | 111.0 | 88 | 34 | 34 | 11 | 37 | 98 | 1 | 0 | 0 | 1 | 10 | 3 | 5 | 3.60 |
| CL | Sanchez, A.Sanchez, Aaron † | Bombers | R | 74.0 | 40 | 0 | 4 | 5 | 3.11 | .291 | 1.21 | 7.6 | 3.3 | 7.6 | 46.1 | 39 | 17 | 16 | 4 | 17 | 39 | 0 | 22 | 3 | 0 | 0 | 1 | 1 | 3.61 |
| SP | Kluber, C.Kluber, Corey † | Suns | R | 72.0 | 21 | 21 | 8 | 7 | 3.24 | .278 | 1.13 | 8.1 | 2.1 | 9.9 | 152.2 | 137 | 63 | 55 | 18 | 36 | 167 | 3 | 0 | 0 | 1 | 13 | 3 | 2 | 3.11 |