| SP | deGrom, J.deGrom, Jacob † | Crabs | R | 118.0 | 21 | 21 | 15 | 4 | 3.08 | .241 | 0.94 | 5.8 | 2.7 | 8.3 | 160.2 | 103 | 56 | 55 | 16 | 48 | 148 | 5 | 0 | 0 | 1 | 14 | 2 | 0 | 3.39 |
| SP | Scherzer, M.Scherzer, Max † | Crabs | R | 117.0 | 20 | 20 | 14 | 1 | 2.52 | .258 | 1.00 | 6.2 | 2.9 | 7.2 | 139.1 | 95 | 41 | 39 | 11 | 45 | 111 | 1 | 0 | 0 | 1 | 15 | 5 | 4 | 3.51 |
| SP | Maddux, G.Maddux, Greg † # | DATA CENTERS | R | 117.0 | 20 | 20 | 13 | 4 | 2.69 | .266 | 1.09 | 8.0 | 1.9 | 5.5 | 150.2 | 133 | 45 | 45 | 9 | 31 | 91 | 10 | 0 | 0 | 5 | 14 | 0 | 2 | 3.19 |
| CL | Chapman, A.Chapman, Aroldis † | Crabs | L | 99.5 | 39 | 0 | 4 | 2 | 0.20 | .177 | 0.64 | 1.8 | 4.0 | 9.4 | 45.0 | 9 | 5 | 1 | 1 | 20 | 47 | 0 | 23 | 1 | 0 | 0 | 0 | 1 | 2.53 |
| SP | Mathewson, C.Mathewson, Christy | Yankees | R | 93.0 | 20 | 20 | 12 | 5 | 2.77 | .253 | 1.00 | 7.1 | 1.9 | 4.6 | 136.2 | 108 | 45 | 42 | 8 | 28 | 69 | 3 | 0 | 0 | 2 | 14 | 3 | 2 | 3.43 |
| SP | Martinez, P.Martinez, Pedro † | Corn Pickers | R | 92.0 | 21 | 21 | 13 | 5 | 3.82 | .292 | 1.21 | 8.2 | 2.6 | 7.9 | 153.1 | 140 | 71 | 65 | 22 | 45 | 134 | 5 | 0 | 0 | 1 | 11 | 5 | 3 | 4.10 |
| SP | Johnson, W.Johnson, Walter | Yankees | R | 80.0 | 21 | 21 | 12 | 5 | 3.56 | .288 | 1.20 | 8.6 | 2.2 | 4.6 | 134.0 | 128 | 53 | 53 | 11 | 33 | 69 | 3 | 0 | 0 | 1 | 14 | 2 | 2 | 3.82 |