| CL | Eckersley, D.Eckersley, Dennis † | Mustangs | R | 106.0 | 46 | 0 | 6 | 2 | 2.92 | .233 | 0.89 | 6.4 | 1.7 | 7.9 | 49.1 | 35 | 16 | 16 | 6 | 9 | 43 | 0 | 28 | 4 | 0 | 0 | 1 | 0 | 3.45 |
| SP | Verlander, J.Verlander, Justin † | Lions | R | 102.0 | 20 | 20 | 11 | 7 | 2.09 | .269 | 1.07 | 7.1 | 2.6 | 8.9 | 150.2 | 118 | 40 | 35 | 11 | 43 | 149 | 1 | 0 | 0 | 0 | 18 | 5 | 2 | 2.93 |
| SP | Arrieta, J.Arrieta, Jake † | Eries | R | 89.0 | 20 | 20 | 10 | 4 | 2.88 | .282 | 1.16 | 7.7 | 2.8 | 8.1 | 147.0 | 125 | 47 | 47 | 12 | 45 | 133 | 2 | 0 | 0 | 0 | 17 | 3 | 1 | 3.23 |
| SP | Maddux, G.Maddux, Greg † # | Cannonballs | R | 87.0 | 19 | 19 | 12 | 5 | 3.97 | .265 | 1.06 | 7.7 | 1.9 | 6.5 | 149.2 | 127 | 70 | 66 | 23 | 32 | 108 | 11 | 0 | 0 | 1 | 11 | 3 | 2 | 4.26 |
| SP | Kershaw, C.Kershaw, Clayton | Militia | L | 82.0 | 20 | 20 | 9 | 8 | 2.72 | .238 | 0.90 | 6.5 | 1.7 | 9.1 | 152.1 | 109 | 46 | 46 | 19 | 28 | 154 | 2 | 0 | 0 | 1 | 16 | 6 | 3 | 3.27 |
| CL | Saito, T.Saito, Takashi † | Militia | R | 81.0 | 38 | 0 | 1 | 2 | 1.10 | .191 | 0.68 | 3.3 | 2.9 | 8.8 | 41.0 | 15 | 5 | 5 | 1 | 13 | 40 | 0 | 24 | 0 | 0 | 0 | 1 | 0 | 2.39 |
| SP | Greinke, Z.Greinke, Zack † | Mud Skippers | R | 77.0 | 19 | 19 | 10 | 2 | 3.39 | .283 | 1.15 | 7.4 | 3.0 | 6.9 | 127.1 | 105 | 49 | 48 | 11 | 42 | 98 | 1 | 0 | 0 | 0 | 12 | 4 | 0 | 3.67 |