| SP | Leonard, D.Leonard, Dutch † | Renegades | L | 168.0 | 28 | 28 | 18 | 3 | 1.92 | .241 | 0.93 | 5.2 | 3.1 | 5.4 | 206.0 | 120 | 49 | 44 | 5 | 71 | 124 | 3 | 0 | 0 | 1 | 23 | 5 | 2 | 3.22 |
| SP | Koufax, S.Koufax, Sandy # | Bulldogs | L | 148.0 | 29 | 29 | 17 | 7 | 3.05 | .275 | 1.11 | 7.6 | 2.4 | 8.3 | 221.0 | 186 | 80 | 75 | 23 | 60 | 205 | 12 | 0 | 0 | 1 | 20 | 5 | 4 | 3.38 |
| SP | Coveleski, S.Coveleski, Stan # | Red Bears | R | 115.0 | 26 | 26 | 17 | 6 | 3.71 | .305 | 1.31 | 8.5 | 3.3 | 4.5 | 186.2 | 176 | 82 | 77 | 13 | 68 | 92 | 5 | 0 | 0 | 4 | 16 | 2 | 2 | 4.05 |
| SP | deGrom, J.deGrom, Jacob † | Artic Wolves | R | 114.0 | 28 | 28 | 15 | 7 | 3.03 | .276 | 1.11 | 7.4 | 2.6 | 8.1 | 178.1 | 146 | 70 | 60 | 16 | 52 | 160 | 1 | 0 | 0 | 1 | 16 | 6 | 0 | 3.35 |
| SP | Mathewson, C.Mathewson, Christy † | Renegades | R | 111.0 | 27 | 27 | 16 | 3 | 3.58 | .297 | 1.26 | 9.3 | 2.1 | 4.6 | 178.1 | 183 | 73 | 71 | 14 | 42 | 91 | 2 | 0 | 0 | 1 | 16 | 1 | 3 | 3.72 |
| SP | Johnson, R.Johnson, Randy # | Renegades | L | 106.0 | 26 | 26 | 14 | 7 | 3.07 | .249 | 0.96 | 6.6 | 2.0 | 7.2 | 176.0 | 130 | 68 | 60 | 15 | 39 | 141 | 2 | 0 | 0 | 0 | 20 | 6 | 1 | 3.27 |
| SP | Alexander, P.Alexander, Pete | Felines | R | 100.0 | 27 | 27 | 15 | 8 | 3.80 | .294 | 1.23 | 8.1 | 3.0 | 5.2 | 187.1 | 168 | 85 | 79 | 20 | 62 | 109 | 5 | 0 | 0 | 3 | 17 | 4 | 4 | 4.28 |
| CL | Feliz, N.Feliz, Neftali † | LIZARDS | R | 99.5 | 70 | 0 | 4 | 4 | 4.48 | .287 | 1.18 | 6.8 | 3.9 | 7.4 | 86.1 | 65 | 45 | 43 | 10 | 37 | 71 | 0 | 33 | 4 | 0 | 0 | 2 | 0 | 4.22 |