| SP | Kershaw, C.Kershaw, Clayton † $ | Cubs | L | 164.5 | 32 | 31 | 17 | 10 | 2.73 | .252 | 0.99 | 7.4 | 1.5 | 7.9 | 250.2 | 206 | 76 | 76 | 20 | 43 | 220 | 15 | 1 | 0 | 2 | 22 | 4 | 4 | 2.84 |
| CL | Doolittle, S.Doolittle, Sean † | Cubs | L | 159.0 | 58 | 0 | 3 | 2 | 1.64 | .206 | 0.76 | 5.0 | 2.0 | 6.3 | 60.1 | 33 | 11 | 11 | 2 | 13 | 42 | 0 | 50 | 2 | 0 | 0 | 1 | 1 | 2.73 |
| SP | Alexander, P.Alexander, Pete † # | Cubs | R | 152.0 | 32 | 32 | 21 | 7 | 3.23 | .257 | 1.02 | 6.8 | 2.3 | 5.2 | 234.1 | 177 | 85 | 84 | 22 | 61 | 134 | 3 | 0 | 0 | 1 | 23 | 5 | 2 | 3.92 |
| SP | McNally, D.McNally, Dave † $$ | Cubs | L | 131.0 | 31 | 31 | 15 | 7 | 3.15 | .267 | 1.09 | 7.3 | 2.5 | 4.8 | 240.1 | 194 | 85 | 84 | 13 | 67 | 128 | 8 | 0 | 0 | 3 | 20 | 2 | 5 | 3.50 |
| SP | Fernandez, S.Fernandez, Sid $$ | Spuds | L | 119.0 | 32 | 32 | 16 | 7 | 3.34 | .280 | 1.13 | 6.8 | 3.4 | 7.5 | 207.1 | 156 | 82 | 77 | 23 | 79 | 173 | 1 | 0 | 0 | 0 | 23 | 7 | 2 | 4.02 |
| SP | Pfiester, J.Pfiester, Jack † # | Cavemen | L | 118.0 | 32 | 32 | 18 | 12 | 3.96 | .290 | 1.20 | 7.9 | 2.9 | 5.0 | 245.1 | 216 | 112 | 108 | 28 | 78 | 136 | 13 | 0 | 0 | 0 | 18 | 6 | 5 | 4.40 |
| SP | Koufax, S.Koufax, Sandy $$ | Raiders | L | 117.0 | 33 | 33 | 15 | 10 | 3.68 | .279 | 1.13 | 7.8 | 2.4 | 8.5 | 247.1 | 214 | 106 | 101 | 23 | 66 | 234 | 5 | 0 | 0 | 2 | 18 | 7 | 4 | 3.20 |
| SP | Richard, J.Richard, J.R. $$ | Vibrators | R | 109.0 | 33 | 33 | 15 | 10 | 3.20 | .283 | 1.17 | 7.0 | 3.6 | 7.5 | 202.1 | 157 | 81 | 72 | 21 | 80 | 169 | 0 | 0 | 0 | 0 | 22 | 2 | 4 | 3.90 |