| SP | Duchscherer, J.Duchscherer, Justin † | Tigers | R | 112.0 | 28 | 28 | 14 | 10 | 2.75 | .271 | 1.05 | 6.9 | 2.6 | 6.2 | 203.0 | 156 | 63 | 62 | 16 | 58 | 139 | 1 | 0 | 0 | 0 | 24 | 12 | 1 | 3.69 |
| SP | Clemens, R.Clemens, Roger # | Wild Cats | R | 111.0 | 29 | 29 | 16 | 7 | 3.42 | .263 | 1.07 | 6.9 | 2.7 | 6.8 | 189.2 | 145 | 72 | 72 | 24 | 57 | 143 | 1 | 0 | 0 | 0 | 19 | 1 | 1 | 4.06 |
| CL | Saito, T.Saito, Takashi † | Dawgz | R | 111.0 | 73 | 0 | 4 | 6 | 3.05 | .248 | 0.93 | 5.8 | 2.6 | 8.8 | 82.2 | 53 | 29 | 28 | 9 | 24 | 80 | 0 | 34 | 5 | 0 | 0 | 5 | 0 | 3.54 |
| SP | Halladay, R.Halladay, Roy † | Dawgz | R | 103.0 | 28 | 28 | 15 | 7 | 3.82 | .303 | 1.27 | 9.5 | 2.0 | 7.4 | 202.2 | 213 | 91 | 86 | 21 | 44 | 167 | 2 | 0 | 0 | 1 | 18 | 7 | 3 | 3.46 |
| SP | Santana, J.Santana, Johan | Bulldogs | L | 98.0 | 29 | 29 | 12 | 10 | 3.43 | .276 | 1.12 | 7.4 | 2.6 | 10.0 | 207.0 | 171 | 83 | 79 | 31 | 60 | 230 | 2 | 0 | 0 | 1 | 20 | 6 | 3 | 3.68 |
| SP | Martinez, P.Martinez, Pedro † $ | Red Sox | R | 94.0 | 29 | 29 | 9 | 7 | 3.08 | .270 | 1.09 | 7.0 | 2.8 | 10.0 | 196.0 | 152 | 71 | 67 | 28 | 61 | 217 | 2 | 0 | 0 | 2 | 21 | 5 | 3 | 3.65 |