| SP | Halladay, R.Halladay, Roy † | Dawgz | R | 94.0 | 23 | 23 | 12 | 4 | 3.59 | .284 | 1.17 | 8.4 | 2.2 | 6.1 | 175.2 | 163 | 73 | 70 | 23 | 42 | 118 | 5 | 0 | 0 | 1 | 16 | 4 | 3 | 4.15 |
| SP | Lincecum, T.Lincecum, Tim † # | Red Tails | R | 93.0 | 26 | 23 | 11 | 5 | 3.41 | .273 | 1.11 | 7.1 | 2.9 | 9.8 | 171.2 | 134 | 66 | 65 | 18 | 56 | 186 | 3 | 0 | 0 | 0 | 15 | 3 | 5 | 3.23 |
| SP | Schmidt, J.Schmidt, Jason | Pigs | R | 90.0 | 24 | 24 | 11 | 5 | 3.63 | .301 | 1.26 | 8.7 | 2.7 | 8.3 | 173.1 | 167 | 74 | 70 | 18 | 52 | 159 | 4 | 0 | 0 | 2 | 14 | 5 | 5 | 3.50 |
| SP | Carpenter, C.Carpenter, Chris † # | Northern Rage | R | 87.0 | 24 | 24 | 10 | 7 | 3.57 | .269 | 1.05 | 7.9 | 1.6 | 5.7 | 189.1 | 166 | 77 | 75 | 25 | 33 | 120 | 10 | 0 | 0 | 1 | 15 | 10 | 1 | 4.13 |
| RP | Saito, T.Saito, Takashi † | Wild Cats | R | 83.0 | 64 | 0 | 8 | 4 | 2.41 | .255 | 1.02 | 6.5 | 2.7 | 8.8 | 93.1 | 67 | 32 | 25 | 14 | 28 | 91 | 0 | 10 | 7 | 0 | 0 | 1 | 0 | 3.94 |
| RP | Broxton, J.Broxton, Jonathan † | Pigs | R | 80.0 | 64 | 0 | 7 | 5 | 2.79 | .316 | 1.34 | 8.2 | 4.0 | 9.9 | 67.2 | 61 | 21 | 21 | 4 | 30 | 74 | 0 | 14 | 2 | 0 | 0 | 3 | 1 | 3.04 |
| SP | Loaiza, E.Loaiza, Esteban # | Eagles | R | 79.0 | 23 | 23 | 12 | 7 | 3.87 | .293 | 1.20 | 8.7 | 2.1 | 6.8 | 158.1 | 153 | 72 | 68 | 24 | 37 | 119 | 4 | 0 | 0 | 1 | 11 | 7 | 3 | 4.30 |