| SP | Koufax, S.Koufax, Sandy † | Grasshoppers | L | 111.0 | 19 | 19 | 12 | 5 | 2.47 | .255 | 1.02 | 6.3 | 2.9 | 8.7 | 149.2 | 104 | 44 | 41 | 15 | 48 | 144 | 7 | 0 | 0 | 1 | 16 | 2 | 3 | 3.38 |
| SP | Leonard, D.Leonard, Dutch † # $ | Warriors | L | 93.0 | 18 | 18 | 12 | 3 | 3.14 | .251 | 1.01 | 6.4 | 2.6 | 6.4 | 126.0 | 90 | 44 | 44 | 7 | 37 | 90 | 3 | 0 | 0 | 3 | 13 | 0 | 0 | 3.17 |
| CL | Chapman, A.Chapman, Aroldis † | Blue Sox | L | 89.5 | 41 | 0 | 5 | 2 | 2.06 | .251 | 0.96 | 5.7 | 3.1 | 11.5 | 43.2 | 27 | 10 | 10 | 4 | 15 | 55 | 0 | 21 | 1 | 0 | 0 | 2 | 1 | 2.84 |
| SP | Martinez, P.Martinez, Pedro † # | EGG | R | 89.0 | 19 | 19 | 11 | 6 | 2.91 | .251 | 0.99 | 7.2 | 1.7 | 9.3 | 136.0 | 109 | 47 | 44 | 12 | 26 | 140 | 4 | 0 | 0 | 0 | 15 | 2 | 1 | 2.71 |
| SP | Alexander, P.Alexander, Pete | Bombers | R | 77.0 | 18 | 18 | 9 | 2 | 2.82 | .266 | 1.06 | 6.9 | 2.6 | 5.7 | 118.0 | 91 | 39 | 37 | 10 | 34 | 75 | 2 | 0 | 0 | 0 | 11 | 3 | 0 | 3.77 |
| SP | deGrom, J.deGrom, Jacob † # | Knights | R | 72.0 | 19 | 19 | 10 | 4 | 3.58 | .279 | 1.14 | 7.8 | 2.4 | 10.0 | 123.1 | 107 | 53 | 49 | 15 | 33 | 137 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.24 |
| SP | Johnson, W.Johnson, Walter | Warriors | R | 72.0 | 19 | 19 | 9 | 5 | 3.46 | .267 | 1.08 | 7.6 | 2.1 | 5.0 | 138.0 | 117 | 53 | 53 | 13 | 32 | 77 | 5 | 0 | 0 | 3 | 11 | 2 | 4 | 3.85 |