| SP | deGrom, J.deGrom, Jacob † | Charlie Browns | R | 115.0 | 24 | 24 | 15 | 5 | 3.10 | .256 | 1.01 | 7.3 | 1.9 | 10.7 | 162.2 | 131 | 61 | 56 | 28 | 34 | 193 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.55 |
| CL | Adams, M.Adams, Mike † $$ | Knights | R | 99.0 | 49 | 0 | 5 | 6 | 2.33 | .264 | 1.07 | 5.8 | 3.8 | 9.3 | 54.0 | 35 | 15 | 14 | 6 | 23 | 56 | 0 | 28 | 4 | 0 | 0 | 0 | 0 | 3.65 |
| SP | Kluber, C.Kluber, Corey # | Ducks | R | 96.0 | 24 | 24 | 11 | 9 | 3.19 | .263 | 1.03 | 6.9 | 2.4 | 10.1 | 172.0 | 132 | 64 | 61 | 23 | 46 | 193 | 6 | 0 | 0 | 3 | 14 | 6 | 1 | 3.40 |
| SP | Scherzer, M.Scherzer, Max † $ | Bengals | R | 95.0 | 24 | 24 | 13 | 6 | 3.68 | .279 | 1.13 | 7.4 | 2.8 | 10.8 | 166.1 | 136 | 75 | 68 | 24 | 52 | 200 | 1 | 0 | 0 | 1 | 14 | 5 | 1 | 3.50 |
| CL | Wagner, B.Wagner, Billy † $ | Creeks | L | 93.0 | 52 | 0 | 3 | 4 | 2.94 | .307 | 1.31 | 8.1 | 3.7 | 9.2 | 49.0 | 44 | 18 | 16 | 5 | 20 | 50 | 0 | 30 | 4 | 0 | 0 | 1 | 0 | 3.57 |
| SP | Verlander, J.Verlander, Justin | BaseBandits | R | 92.0 | 24 | 24 | 12 | 11 | 3.26 | .286 | 1.16 | 7.6 | 2.8 | 9.7 | 171.0 | 145 | 63 | 62 | 30 | 54 | 185 | 6 | 0 | 0 | 0 | 18 | 6 | 4 | 4.17 |