| SP | Santana, J.Santana, Johan † | Blazers | L | 334.0 | 51 | 51 | 35 | 10 | 2.13 | .249 | 0.97 | 6.7 | 2.1 | 8.6 | 396.1 | 295 | 105 | 94 | 19 | 91 | 378 | 19 | 0 | 0 | 3 | 0 | 9 | 9 | 2.47 |
| SP | Martinez, P.Martinez, Pedro † | Padres | R | 215.0 | 47 | 47 | 25 | 8 | 2.85 | .277 | 1.15 | 8.0 | 2.3 | 9.5 | 315.1 | 281 | 109 | 100 | 20 | 81 | 332 | 2 | 0 | 0 | 2 | 0 | 1 | 3 | 2.50 |
| RP | Gossage, R.Gossage, Rich † | Rockies | R | 202.0 | 93 | 0 | 16 | 2 | 1.57 | .217 | 0.81 | 4.7 | 2.6 | 9.3 | 206.0 | 107 | 38 | 36 | 8 | 59 | 214 | 0 | 14 | 4 | 0 | 0 | 5 | 4 | 2.36 |
| SP | Marichal, J.Marichal, Juan † | Pilots | R | 201.0 | 47 | 47 | 22 | 17 | 3.05 | .269 | 1.08 | 7.6 | 2.1 | 5.9 | 363.0 | 308 | 146 | 123 | 34 | 85 | 238 | 26 | 0 | 0 | 2 | 0 | 7 | 6 | 3.67 |
| RP | Lockwood, S.Lockwood, Skip † | Rockies | R | 182.0 | 91 | 0 | 15 | 5 | 1.72 | .234 | 0.92 | 4.9 | 3.3 | 8.4 | 178.0 | 97 | 34 | 34 | 13 | 66 | 166 | 0 | 18 | 5 | 0 | 0 | 0 | 6 | 3.20 |
| SP | Santana, E.Santana, Ervin † | Rockies | R | 178.0 | 49 | 49 | 26 | 16 | 3.56 | .280 | 1.15 | 7.6 | 2.7 | 6.6 | 325.2 | 276 | 130 | 129 | 35 | 98 | 238 | 8 | 0 | 0 | 2 | 0 | 6 | 5 | 3.90 |
| SP | Fernandez, S.Fernandez, Sid | Diamond Cats | L | 173.0 | 46 | 46 | 19 | 12 | 2.73 | .273 | 1.12 | 6.4 | 3.7 | 8.1 | 310.0 | 221 | 96 | 94 | 23 | 126 | 279 | 1 | 0 | 0 | 0 | 0 | 3 | 1 | 3.41 |
| SP | Siebert, S.Siebert, Sonny † | Brujos | R | 163.0 | 47 | 47 | 19 | 11 | 3.21 | .270 | 1.10 | 7.5 | 2.4 | 5.5 | 333.1 | 279 | 121 | 119 | 29 | 87 | 204 | 6 | 0 | 0 | 1 | 0 | 3 | 6 | 3.72 |