| SP | deGrom, J.deGrom, Jacob † $$ | Warriors | R | 96.0 | 19 | 19 | 12 | 4 | 2.89 | .250 | 0.98 | 6.5 | 2.4 | 10.7 | 130.2 | 94 | 44 | 42 | 14 | 34 | 155 | 1 | 0 | 0 | 1 | 16 | 3 | 0 | 2.87 |
| SP | Greinke, Z.Greinke, Zack † | Vikings | R | 76.0 | 19 | 19 | 10 | 5 | 3.37 | .284 | 1.16 | 7.4 | 3.0 | 7.4 | 136.1 | 112 | 53 | 51 | 18 | 46 | 112 | 3 | 0 | 0 | 0 | 12 | 4 | 3 | 4.18 |
| CL | Jansen, K.Jansen, Kenley † | Cyclones | R | 73.0 | 39 | 0 | 1 | 3 | 2.20 | .259 | 1.02 | 6.4 | 2.9 | 9.9 | 41.0 | 29 | 10 | 10 | 5 | 13 | 45 | 0 | 24 | 1 | 0 | 0 | 1 | 0 | 3.41 |
| SP | Santana, J.Santana, Johan # | Warriors | L | 70.0 | 18 | 18 | 10 | 4 | 3.86 | .266 | 1.07 | 7.1 | 2.6 | 9.4 | 126.0 | 99 | 54 | 54 | 24 | 36 | 131 | 2 | 0 | 0 | 0 | 10 | 2 | 1 | 4.30 |
| SP | Tanana, F.Tanana, Frank † | Isotopes | L | 69.0 | 17 | 17 | 10 | 5 | 3.76 | .304 | 1.29 | 8.9 | 2.8 | 7.3 | 124.1 | 122 | 58 | 52 | 16 | 38 | 100 | 4 | 0 | 0 | 1 | 9 | 3 | 4 | 4.06 |
| CL | Edwards, C.Edwards, Carl † | Lost Cubs | R | 67.0 | 26 | 0 | 1 | 0 | 1.30 | .231 | 0.90 | 4.0 | 4.3 | 12.3 | 27.2 | 12 | 4 | 4 | 1 | 13 | 37 | 0 | 20 | 2 | 0 | 0 | 0 | 2 | 2.19 |
| CL | Street, H.Street, Huston † | Chiefs | R | 62.0 | 35 | 0 | 2 | 3 | 1.93 | .279 | 1.13 | 5.3 | 5.1 | 9.0 | 32.2 | 19 | 10 | 7 | 2 | 18 | 32 | 0 | 20 | 4 | 0 | 0 | 1 | 0 | 3.59 |