| SP | Martinez, P.Martinez, Pedro † | Slingers | R | 160.0 | 29 | 29 | 15 | 8 | 2.21 | .250 | 0.97 | 7.0 | 1.7 | 10.1 | 223.2 | 173 | 64 | 55 | 15 | 43 | 250 | 10 | 0 | 0 | 3 | 24 | 8 | 1 | 2.32 |
| CL | Balfour, G.Balfour, Grant † | Gems | R | 124.5 | 58 | 0 | 6 | 4 | 3.13 | .284 | 1.15 | 6.8 | 3.7 | 11.0 | 54.2 | 41 | 21 | 19 | 5 | 22 | 66 | 0 | 35 | 1 | 0 | 0 | 2 | 0 | 3.09 |
| SP | Halladay, R.Halladay, Roy † $ | Gems | R | 113.0 | 28 | 28 | 14 | 5 | 3.67 | .294 | 1.21 | 8.7 | 2.2 | 6.6 | 203.2 | 197 | 83 | 83 | 20 | 50 | 149 | 9 | 0 | 0 | 3 | 16 | 7 | 3 | 3.66 |
| CL | Rivera, M.Rivera, Mariano † $$ | Wallbangers | R | 109.0 | 52 | 0 | 3 | 3 | 2.67 | .252 | 0.94 | 7.4 | 1.1 | 7.9 | 57.1 | 47 | 17 | 17 | 5 | 7 | 50 | 0 | 34 | 3 | 0 | 0 | 4 | 0 | 2.96 |
| CL | Hoffman, T.Hoffman, Trevor † | Dragons | R | 102.5 | 66 | 0 | 4 | 3 | 3.19 | .295 | 1.24 | 7.4 | 3.8 | 8.1 | 73.1 | 60 | 29 | 26 | 7 | 31 | 66 | 0 | 29 | 3 | 0 | 0 | 1 | 1 | 3.75 |
| SP | Lincecum, T.Lincecum, Tim | Mountain Lions | R | 94.0 | 29 | 29 | 13 | 9 | 3.75 | .297 | 1.25 | 7.9 | 3.3 | 9.7 | 197.0 | 173 | 89 | 82 | 24 | 73 | 212 | 2 | 0 | 0 | 1 | 15 | 4 | 7 | 3.60 |