| SP | Wilhelm, H.Wilhelm, Hoyt $ | Indians | R | 78.0 | 16 | 16 | 11 | 3 | 3.27 | .294 | 1.25 | 7.6 | 3.7 | 4.2 | 113.0 | 95 | 45 | 41 | 7 | 46 | 53 | 2 | 0 | 0 | 2 | 10 | 0 | 4 | 4.09 |
| CL | Staley, J.Staley, Jerry $ | White Sox | R | 78.0 | 28 | 0 | 7 | 3 | 1.72 | .288 | 1.21 | 8.4 | 2.6 | 4.1 | 31.1 | 29 | 8 | 6 | 3 | 9 | 14 | 0 | 16 | 3 | 0 | 0 | 0 | 0 | 4.23 |
| CL | Fornieles, M.Fornieles, Mike $ | Red Sox | R | 58.5 | 24 | 0 | 4 | 2 | 2.49 | .303 | 1.30 | 8.3 | 3.6 | 4.0 | 25.1 | 23 | 8 | 7 | 3 | 10 | 11 | 0 | 15 | 1 | 0 | 0 | 0 | 1 | 4.88 |
| RP | Sturdivant, T.Sturdivant, Tom $ | Yankees | R | 53.0 | 28 | 0 | 6 | 0 | 1.58 | .269 | 1.09 | 6.5 | 3.3 | 5.8 | 57.0 | 41 | 10 | 10 | 3 | 21 | 37 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 3.54 |
| SP | Pierce, B.Pierce, Billy $ | White Sox | L | 52.0 | 15 | 15 | 7 | 3 | 3.31 | .302 | 1.30 | 8.9 | 2.8 | 5.0 | 103.1 | 102 | 41 | 38 | 11 | 32 | 57 | 0 | 0 | 0 | 0 | 11 | 0 | 0 | 4.21 |
| SP | Casale, J.Casale, Jerry $ | Red Sox | R | 47.0 | 16 | 16 | 7 | 5 | 3.14 | .319 | 1.40 | 7.2 | 5.4 | 5.4 | 91.2 | 73 | 38 | 32 | 6 | 55 | 55 | 0 | 0 | 0 | 0 | 10 | 1 | 2 | 4.49 |
| RP | Clevenger, T.Clevenger, Tex $ | Senators | R | 39.0 | 32 | 0 | 5 | 0 | 3.48 | .357 | 1.66 | 10.1 | 5.1 | 5.5 | 51.2 | 57 | 28 | 20 | 2 | 29 | 31 | 0 | 2 | 1 | 0 | 0 | 0 | 4 | 4.00 |