| SP | Scherzer, M.Scherzer, Max † | Bees | R | 177.0 | 71 | 0 | 26 | 5 | 2.82 | .276 | 1.13 | 7.8 | 2.4 | 9.0 | 165.2 | 143 | 56 | 52 | 11 | 44 | 165 | 0 | 2 | 0 | 0 | 0 | 2 | 4 | 2.70 |
| SP | Richard, J.Richard, J.R. † | Colt 45s | R | 153.0 | 32 | 32 | 17 | 10 | 2.68 | .288 | 1.19 | 6.7 | 4.0 | 8.2 | 245.1 | 183 | 76 | 73 | 16 | 109 | 224 | 5 | 0 | 0 | 2 | 23 | 6 | 0 | 3.43 |
| SP | Martinez, P.Martinez, Pedro | Red Sox | R | 131.0 | 36 | 36 | 15 | 17 | 3.12 | .278 | 1.11 | 7.4 | 2.6 | 9.4 | 271.1 | 223 | 97 | 94 | 25 | 79 | 284 | 9 | 0 | 0 | 2 | 24 | 11 | 2 | 3.10 |
| RP | Wagner, B.Wagner, Billy † # | Colt 45s | L | 126.0 | 105 | 0 | 17 | 8 | 3.43 | .267 | 1.07 | 6.2 | 3.5 | 9.2 | 165.1 | 113 | 64 | 63 | 16 | 64 | 169 | 0 | 8 | 5 | 0 | 0 | 4 | 2 | 3.45 |
| SP | Kershaw, C.Kershaw, Clayton | Bees | L | 122.0 | 36 | 31 | 14 | 10 | 3.50 | .264 | 1.07 | 7.9 | 1.7 | 9.2 | 221.0 | 194 | 86 | 86 | 15 | 42 | 225 | 11 | 2 | 1 | 3 | 19 | 2 | 5 | 2.44 |
| CL | Doolittle, S.Doolittle, Sean † | Nationals 4 | L | 122.0 | 72 | 0 | 4 | 5 | 2.24 | .265 | 1.06 | 7.3 | 2.3 | 9.2 | 84.1 | 68 | 22 | 21 | 6 | 21 | 86 | 0 | 34 | 5 | 0 | 0 | 2 | 1 | 2.70 |
| RP | Borucki, R.Borucki, Ryan † | Pirat13s | L | 121.0 | 82 | 0 | 18 | 3 | 3.03 | .271 | 1.10 | 7.5 | 2.4 | 6.5 | 113.0 | 94 | 43 | 38 | 9 | 30 | 81 | 0 | 4 | 3 | 0 | 0 | 2 | 3 | 3.45 |