| SP | Duchscherer, J.Duchscherer, Justin † | Dragons | R | 118.0 | 23 | 23 | 14 | 2 | 2.73 | .264 | 1.04 | 7.1 | 2.4 | 5.9 | 171.2 | 134 | 58 | 52 | 20 | 45 | 112 | 0 | 0 | 0 | 0 | 19 | 6 | 4 | 4.11 |
| SP | Schilling, C.Schilling, Curt † # | Horses | R | 85.0 | 24 | 24 | 11 | 8 | 3.84 | .295 | 1.25 | 8.5 | 2.7 | 10.4 | 168.2 | 159 | 77 | 72 | 19 | 51 | 195 | 7 | 0 | 0 | 2 | 12 | 2 | 2 | 3.10 |
| SP | Santana, J.Santana, Johan | Yard Birds | L | 77.0 | 24 | 24 | 12 | 9 | 3.94 | .282 | 1.15 | 7.7 | 2.6 | 9.4 | 153.0 | 131 | 70 | 67 | 25 | 45 | 159 | 2 | 0 | 0 | 2 | 15 | 4 | 6 | 4.01 |
| SP | Zambrano, C.Zambrano, Carlos † # | Dragons | R | 75.0 | 23 | 23 | 11 | 11 | 3.47 | .294 | 1.22 | 7.9 | 3.2 | 6.3 | 168.2 | 147 | 76 | 65 | 19 | 59 | 117 | 3 | 0 | 0 | 2 | 16 | 5 | 3 | 4.22 |
| RP | Springer, R.Springer, Russ | Sharks | R | 74.0 | 55 | 0 | 6 | 1 | 2.00 | .266 | 1.05 | 6.8 | 2.8 | 7.9 | 85.2 | 64 | 19 | 19 | 9 | 26 | 75 | 0 | 6 | 3 | 0 | 0 | 3 | 2 | 3.64 |
| SP | Martinez, P.Martinez, Pedro † | Ducks | R | 69.0 | 24 | 24 | 11 | 10 | 4.03 | .304 | 1.27 | 8.0 | 3.4 | 8.5 | 169.2 | 151 | 77 | 76 | 24 | 64 | 159 | 3 | 0 | 0 | 1 | 14 | 7 | 2 | 4.22 |
| CL | Papelbon, J.Papelbon, Jonathan † | Horses | R | 67.0 | 48 | 0 | 3 | 5 | 3.00 | .282 | 1.18 | 8.2 | 2.4 | 8.1 | 57.0 | 52 | 19 | 19 | 7 | 15 | 51 | 0 | 20 | 4 | 0 | 0 | 0 | 0 | 3.60 |
| SP | Burnett, A.Burnett, A.J. # | Sharks | R | 65.0 | 23 | 23 | 13 | 7 | 4.82 | .321 | 1.39 | 8.4 | 4.1 | 7.9 | 145.2 | 136 | 79 | 78 | 18 | 66 | 127 | 1 | 0 | 0 | 1 | 10 | 5 | 3 | 4.33 |