| SP | Pivetta, N.Pivetta, Nick † | Eagles | R | 97.0 | 22 | 22 | 12 | 5 | 3.05 | .265 | 1.04 | 6.5 | 2.9 | 10.9 | 147.1 | 106 | 50 | 50 | 17 | 47 | 178 | 1 | 0 | 0 | 1 | 14 | 6 | 2 | 3.16 |
| CL | Suarez, R.Suarez, Robert † | Pirates | R | 88.0 | 59 | 0 | 5 | 3 | 2.98 | .307 | 1.26 | 8.7 | 2.7 | 11.0 | 63.1 | 61 | 26 | 21 | 10 | 19 | 77 | 0 | 20 | 1 | 0 | 0 | 4 | 0 | 3.71 |
| RP | Svanson, M.Svanson, Matt † | Outlaws | R | 85.0 | 55 | 0 | 10 | 2 | 3.04 | .280 | 1.17 | 6.6 | 4.0 | 11.1 | 97.2 | 71 | 33 | 33 | 9 | 43 | 120 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.06 |
| RP | Rodríguez, R.Rodríguez, Randy | Sloths | R | 69.5 | 54 | 0 | 8 | 1 | 2.42 | .232 | 0.91 | 5.7 | 2.6 | 10.9 | 81.2 | 51 | 22 | 22 | 7 | 23 | 98 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 2.56 |
| SP | Skubal, T.Skubal, Tarik † | Eruptions | L | 66.0 | 22 | 22 | 10 | 6 | 3.96 | .303 | 1.27 | 9.2 | 2.3 | 12.3 | 129.2 | 132 | 57 | 57 | 13 | 33 | 177 | 0 | 0 | 0 | 0 | 8 | 4 | 2 | 2.43 |
| SP | Eovaldi, N.Eovaldi, Nathan # | Lions | R | 65.0 | 22 | 22 | 9 | 9 | 3.64 | .260 | 1.04 | 7.2 | 2.2 | 9.7 | 146.0 | 117 | 60 | 59 | 20 | 35 | 158 | 2 | 0 | 0 | 1 | 12 | 2 | 6 | 3.38 |
| SP | Crochet, G.Crochet, Garrett # | Fighting Pigs | L | 64.0 | 21 | 21 | 10 | 6 | 4.17 | .305 | 1.29 | 9.7 | 2.0 | 10.2 | 138.0 | 148 | 68 | 64 | 16 | 30 | 156 | 1 | 0 | 0 | 0 | 13 | 4 | 3 | 2.99 |