| SP | Sanchez, C.Sanchez, Cristopher † | Bees | L | 129.0 | 33 | 33 | 16 | 5 | 3.39 | .305 | 1.29 | 8.6 | 3.0 | 10.5 | 210.0 | 200 | 83 | 79 | 21 | 70 | 246 | 2 | 0 | 0 | 0 | 20 | 6 | 3 | 3.04 |
| SP | Skubal, T.Skubal, Tarik # | Elephants | L | 119.0 | 35 | 35 | 17 | 10 | 3.77 | .279 | 1.14 | 8.4 | 1.9 | 10.1 | 227.0 | 211 | 95 | 95 | 28 | 48 | 255 | 1 | 0 | 0 | 1 | 21 | 4 | 6 | 3.04 |
| RP | Santillan, T.Santillan, Tony † | Spiders | R | 113.5 | 86 | 0 | 11 | 2 | 2.39 | .304 | 1.27 | 7.5 | 4.0 | 9.4 | 109.1 | 91 | 29 | 29 | 7 | 48 | 114 | 0 | 11 | 5 | 0 | 0 | 4 | 6 | 3.17 |
| CL | Chapman, A.Chapman, Aroldis † | Elephants | L | 110.0 | 78 | 0 | 5 | 7 | 3.76 | .311 | 1.32 | 7.9 | 4.0 | 12.3 | 81.1 | 71 | 36 | 34 | 10 | 36 | 111 | 0 | 34 | 6 | 0 | 0 | 3 | 6 | 3.31 |
| SP | Eovaldi, N.Eovaldi, Nathan † | Spiders | R | 106.0 | 36 | 36 | 16 | 12 | 3.78 | .277 | 1.12 | 8.0 | 2.1 | 8.6 | 235.2 | 210 | 99 | 99 | 28 | 54 | 225 | 1 | 0 | 0 | 0 | 24 | 7 | 7 | 3.41 |