| SP | Skubal, T.Skubal, Tarik † | Phucketts | L | 99.0 | 20 | 20 | 10 | 6 | 2.16 | .248 | 0.95 | 6.4 | 2.2 | 10.7 | 141.2 | 100 | 38 | 34 | 8 | 35 | 167 | 2 | 0 | 0 | 2 | 17 | 5 | 1 | 2.22 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu | Eruptions | R | 83.0 | 20 | 20 | 10 | 5 | 2.60 | .256 | 0.99 | 6.2 | 2.8 | 10.4 | 121.1 | 83 | 38 | 35 | 12 | 37 | 140 | 0 | 0 | 0 | 0 | 12 | 5 | 1 | 3.02 |
| SP | Eovaldi, N.Eovaldi, Nathan † | Suns | R | 81.0 | 20 | 20 | 10 | 6 | 2.69 | .252 | 1.01 | 6.3 | 2.8 | 8.7 | 130.1 | 91 | 50 | 39 | 13 | 40 | 126 | 0 | 0 | 0 | 0 | 13 | 1 | 7 | 3.31 |
| SP | Pivetta, N.Pivetta, Nick † | Scooters | R | 80.0 | 20 | 20 | 11 | 6 | 2.96 | .282 | 1.15 | 7.1 | 3.3 | 9.4 | 124.2 | 98 | 43 | 41 | 10 | 45 | 129 | 0 | 0 | 0 | 0 | 15 | 4 | 4 | 3.15 |
| SP | Glasnow, T.Glasnow, Tyler † | Phucketts | R | 80.0 | 18 | 18 | 10 | 1 | 2.96 | .266 | 1.07 | 6.3 | 3.3 | 10.9 | 100.1 | 70 | 33 | 33 | 10 | 37 | 121 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 3.05 |
| CL | Chapman, A.Chapman, Aroldis † | Phucketts | L | 80.0 | 47 | 0 | 0 | 2 | 2.37 | .271 | 1.07 | 5.9 | 3.9 | 10.8 | 49.1 | 32 | 13 | 13 | 5 | 21 | 59 | 0 | 28 | 4 | 0 | 0 | 2 | 2 | 3.33 |
| SP | Littell, Z.Littell, Zack † | Fighting Pigs | R | 74.0 | 19 | 19 | 9 | 3 | 2.86 | .285 | 1.19 | 8.4 | 2.4 | 6.7 | 122.2 | 114 | 40 | 39 | 14 | 32 | 91 | 0 | 0 | 0 | 0 | 13 | 1 | 1 | 3.81 |