| SP | Skubal, T.Skubal, Tarik † $$ | Bees | L | 182.0 | 34 | 34 | 23 | 8 | 3.18 | .272 | 1.10 | 7.5 | 2.5 | 10.7 | 243.2 | 202 | 91 | 86 | 23 | 67 | 289 | 6 | 0 | 0 | 4 | 25 | 4 | 2 | 2.73 |
| CL | Okert, S.Okert, Steven $$ | Pilots | L | 147.5 | 65 | 0 | 5 | 4 | 1.64 | .277 | 1.12 | 7.0 | 3.1 | 10.2 | 66.0 | 51 | 14 | 12 | 5 | 23 | 75 | 0 | 41 | 2 | 0 | 0 | 2 | 0 | 2.85 |
| CL | Chapman, A.Chapman, Aroldis † | Alleganies2099⚾ | L | 132.0 | 67 | 0 | 3 | 2 | 1.92 | .189 | 0.69 | 4.3 | 1.9 | 11.5 | 65.2 | 31 | 14 | 14 | 4 | 14 | 83 | 0 | 38 | 2 | 0 | 0 | 1 | 3 | 1.94 |
| SP | Eovaldi, N.Eovaldi, Nathan † | Tigers | R | 130.0 | 34 | 34 | 15 | 9 | 2.79 | .270 | 1.09 | 7.5 | 2.3 | 8.9 | 226.0 | 188 | 76 | 70 | 23 | 59 | 224 | 0 | 0 | 0 | 0 | 26 | 4 | 6 | 3.18 |
| SP | Schwellenbach, S.Schwellenbach, Spencer † # | Tigers | R | 112.0 | 33 | 33 | 14 | 10 | 3.39 | .287 | 1.18 | 8.5 | 2.2 | 8.0 | 230.2 | 216 | 87 | 87 | 27 | 56 | 204 | 3 | 0 | 0 | 2 | 23 | 7 | 1 | 3.57 |