| SP | Mathewson, C.Mathewson, Christy † # | Giants | R | 90.0 | 17 | 17 | 10 | 5 | 2.76 | .235 | 0.92 | 6.5 | 1.8 | 5.0 | 140.1 | 101 | 45 | 43 | 10 | 28 | 77 | 8 | 0 | 0 | 2 | 13 | 0 | 1 | 3.43 |
| CL | Wagner, B.Wagner, Billy † | Astros | L | 79.0 | 33 | 0 | 5 | 3 | 2.56 | .307 | 1.33 | 7.5 | 4.6 | 8.7 | 31.2 | 26 | 9 | 9 | 1 | 16 | 30 | 0 | 20 | 0 | 0 | 0 | 0 | 2 | 3.03 |
| SP | Kershaw, C.Kershaw, Clayton † # | Champs | L | 75.0 | 17 | 17 | 9 | 3 | 3.31 | .254 | 1.01 | 7.6 | 1.6 | 10.3 | 114.1 | 96 | 42 | 42 | 11 | 20 | 131 | 4 | 0 | 0 | 1 | 12 | 1 | 3 | 2.51 |
| CL | Robertson, D.Robertson, David † | Rays | R | 72.5 | 38 | 0 | 3 | 1 | 2.04 | .300 | 1.29 | 5.8 | 6.0 | 7.6 | 39.2 | 25 | 12 | 9 | 2 | 26 | 33 | 0 | 19 | 2 | 0 | 0 | 0 | 6 | 3.97 |
| SP | McClanahan, S.McClanahan, Shane # | Diamondbacks | L | 66.0 | 17 | 17 | 7 | 4 | 2.77 | .269 | 1.09 | 7.2 | 2.6 | 7.6 | 117.0 | 94 | 37 | 36 | 12 | 34 | 99 | 1 | 0 | 0 | 1 | 13 | 1 | 0 | 3.54 |