| SP | Maddux, G.Maddux, Greg † # | Braves | R | 155.0 | 22 | 22 | 18 | 2 | 2.77 | .253 | 1.01 | 7.6 | 1.5 | 5.4 | 179.0 | 151 | 55 | 55 | 9 | 30 | 108 | 13 | 0 | 0 | 3 | 14 | 1 | 4 | 2.97 |
| SP | Rodon, C.Rodon, Carlos † # | Sox | L | 113.0 | 22 | 22 | 15 | 3 | 2.82 | .266 | 1.08 | 7.7 | 2.1 | 9.1 | 137.1 | 117 | 46 | 43 | 19 | 32 | 138 | 0 | 0 | 0 | 0 | 17 | 0 | 2 | 3.49 |
| SP | Bender, C.Bender, Chief † | A’s | R | 107.0 | 21 | 21 | 15 | 5 | 3.71 | .307 | 1.30 | 8.6 | 3.1 | 6.3 | 162.1 | 155 | 70 | 67 | 18 | 56 | 114 | 9 | 0 | 0 | 1 | 13 | 5 | 4 | 4.17 |
| SP | Krause, H.Krause, Harry † # | A’s | L | 104.0 | 21 | 21 | 12 | 4 | 2.89 | .248 | 0.98 | 5.9 | 2.9 | 5.9 | 161.2 | 106 | 54 | 52 | 11 | 52 | 106 | 4 | 0 | 0 | 3 | 15 | 2 | 3 | 3.58 |
| SP | Morton, C.Morton, Charlie | Braves | R | 91.0 | 22 | 22 | 13 | 3 | 3.41 | .290 | 1.20 | 8.0 | 2.9 | 7.3 | 134.2 | 119 | 56 | 51 | 14 | 43 | 109 | 0 | 0 | 0 | 0 | 13 | 3 | 1 | 3.76 |
| SP | Kluber, C.Kluber, Corey # | Indians | R | 90.0 | 22 | 22 | 12 | 5 | 4.06 | .279 | 1.13 | 8.6 | 1.6 | 9.4 | 162.0 | 154 | 75 | 73 | 20 | 29 | 170 | 6 | 0 | 0 | 3 | 13 | 5 | 2 | 3.14 |
| SP | McKenzie, T.McKenzie, Triston | Indians | R | 84.0 | 21 | 21 | 15 | 3 | 4.42 | .317 | 1.36 | 9.4 | 2.9 | 6.2 | 134.1 | 140 | 69 | 66 | 23 | 43 | 93 | 0 | 0 | 0 | 0 | 8 | 4 | 4 | 4.90 |