| SP | Skubal, T.Skubal, Tarik † # | T11gers | L | 126.0 | 24 | 24 | 14 | 3 | 2.65 | .248 | 0.95 | 6.5 | 2.1 | 9.7 | 176.2 | 127 | 52 | 52 | 11 | 41 | 189 | 2 | 0 | 0 | 0 | 17 | 7 | 2 | 2.48 |
| SP | Scherzer, M.Scherzer, Max † | Mets | R | 109.0 | 24 | 24 | 13 | 5 | 3.16 | .266 | 1.06 | 7.0 | 2.6 | 9.2 | 171.0 | 133 | 63 | 60 | 19 | 49 | 174 | 3 | 0 | 0 | 2 | 17 | 4 | 3 | 3.34 |
| SP | Schupp, F.Schupp, Ferdie † | Cubbies | L | 108.0 | 25 | 25 | 12 | 2 | 1.95 | .239 | 0.91 | 5.9 | 2.3 | 5.2 | 138.1 | 91 | 33 | 30 | 13 | 35 | 79 | 0 | 0 | 0 | 0 | 9 | 4 | 0 | 3.93 |
| SP | Fisher, B.Fisher, Braydon | Blue Jays | R | 98.0 | 47 | 0 | 16 | 3 | 2.57 | .263 | 1.06 | 5.8 | 3.8 | 8.4 | 73.2 | 47 | 24 | 21 | 6 | 31 | 68 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Benoit, J.Benoit, Joaquin † | Devil Rays | R | 96.0 | 72 | 0 | 8 | 2 | 1.66 | .245 | 0.97 | 6.8 | 2.0 | 7.8 | 81.1 | 61 | 17 | 15 | 7 | 18 | 70 | 0 | 10 | 0 | 0 | 0 | 0 | 1 | 3.06 |
| SP | McClanahan, S.McClanahan, Shane | Devil Rays | L | 94.0 | 24 | 24 | 12 | 9 | 2.88 | .261 | 1.05 | 6.4 | 3.0 | 8.2 | 162.1 | 116 | 53 | 52 | 18 | 54 | 147 | 1 | 0 | 0 | 1 | 18 | 2 | 6 | 3.67 |