| SP | Darvish, Y.Darvish, Yu † # | Rangers | R | 155.0 | 37 | 37 | 21 | 11 | 3.18 | .282 | 1.15 | 7.1 | 3.3 | 8.7 | 254.2 | 201 | 93 | 90 | 25 | 93 | 246 | 1 | 0 | 0 | 0 | 24 | 6 | 4 | 3.51 |
| SP | Chamberlain, E.Chamberlain, Elton # | Pitch Fever | R | 152.0 | 35 | 35 | 19 | 6 | 3.38 | .283 | 1.17 | 7.6 | 2.9 | 4.6 | 255.2 | 216 | 100 | 96 | 16 | 83 | 130 | 12 | 0 | 0 | 2 | 21 | 3 | 0 | 3.81 |
| CL | Helsley, R.Helsley, Ryan † | Pitch Fever | R | 144.0 | 74 | 0 | 1 | 1 | 3.58 | .307 | 1.32 | 8.4 | 3.5 | 9.6 | 73.0 | 68 | 29 | 29 | 10 | 28 | 78 | 0 | 52 | 6 | 0 | 0 | 1 | 0 | 3.84 |
| SP | Johnson, J.Johnson, Josh † | Marlins | R | 143.0 | 65 | 0 | 21 | 2 | 3.04 | .313 | 1.33 | 7.2 | 4.9 | 5.5 | 159.2 | 127 | 60 | 54 | 14 | 86 | 97 | 0 | 0 | 0 | 0 | 0 | 5 | 3 | 4.64 |
| SP | Schmidt, J.Schmidt, Jason | Giants | R | 130.0 | 36 | 36 | 17 | 14 | 3.38 | .279 | 1.13 | 7.3 | 2.9 | 7.7 | 263.1 | 214 | 104 | 99 | 24 | 84 | 224 | 7 | 0 | 0 | 1 | 22 | 7 | 10 | 3.52 |
| SP | Scherzer, M.Scherzer, Max | Rangers | R | 128.0 | 53 | 0 | 18 | 1 | 2.86 | .307 | 1.29 | 7.2 | 4.5 | 7.8 | 132.1 | 105 | 50 | 42 | 8 | 66 | 115 | 0 | 0 | 0 | 0 | 0 | 5 | 4 | 3.66 |
| SP | Fernandez, J.Fernandez, Jose # | Marlins | R | 125.0 | 34 | 34 | 16 | 6 | 3.40 | .281 | 1.16 | 7.4 | 3.1 | 7.9 | 222.1 | 182 | 88 | 84 | 25 | 76 | 194 | 1 | 0 | 0 | 1 | 25 | 3 | 2 | 3.78 |
| SP | Flaherty, J.Flaherty, Jack | Pitch Fever | R | 116.0 | 34 | 34 | 15 | 9 | 3.07 | .288 | 1.21 | 7.3 | 3.6 | 8.7 | 202.1 | 163 | 75 | 69 | 16 | 81 | 195 | 0 | 0 | 0 | 0 | 24 | 1 | 2 | 3.32 |