| SP | Newhouser, H.Newhouser, Hal † | Tigers | L | 230.0 | 41 | 41 | 30 | 6 | 2.97 | .289 | 1.21 | 7.6 | 3.3 | 4.9 | 312.0 | 262 | 113 | 103 | 22 | 115 | 171 | 7 | 0 | 0 | 1 | 30 | 3 | 9 | 3.96 |
| SP | Feller, B.Feller, Bob † # | Indians | R | 168.0 | 39 | 39 | 18 | 11 | 2.90 | .286 | 1.20 | 7.8 | 3.1 | 5.0 | 298.0 | 257 | 116 | 96 | 15 | 101 | 165 | 13 | 0 | 0 | 5 | 26 | 0 | 3 | 3.56 |
| SP | Chandler, S.Chandler, Spud † | Yankees | R | 147.0 | 38 | 38 | 18 | 11 | 3.17 | .305 | 1.31 | 7.7 | 4.2 | 3.5 | 280.2 | 238 | 117 | 99 | 11 | 131 | 109 | 11 | 0 | 0 | 3 | 27 | 0 | 7 | 4.14 |
| SP | Hutchinson, F.Hutchinson, Fred † | Tigers | R | 140.0 | 40 | 40 | 18 | 13 | 3.24 | .277 | 1.15 | 7.4 | 3.0 | 4.3 | 300.1 | 245 | 116 | 108 | 17 | 101 | 142 | 6 | 0 | 0 | 1 | 27 | 0 | 0 | 3.80 |
| CL | Pierce, B.Pierce, Billy † | Tigers | L | 109.5 | 58 | 0 | 1 | 5 | 3.66 | .346 | 1.59 | 8.6 | 5.8 | 4.2 | 51.2 | 49 | 25 | 21 | 3 | 33 | 24 | 0 | 45 | 7 | 0 | 0 | 0 | 1 | 4.76 |
| SP | Parnell, M.Parnell, Mel † | Red Sox | L | 107.0 | 40 | 40 | 20 | 18 | 4.38 | .325 | 1.44 | 8.6 | 4.3 | 3.4 | 291.2 | 279 | 151 | 142 | 29 | 140 | 110 | 13 | 0 | 0 | 2 | 21 | 3 | 8 | 5.01 |