| SP | Gooden, D.Gooden, Dwight † | Aces Eights | R | 129.0 | 27 | 27 | 19 | 4 | 3.81 | .310 | 1.34 | 8.7 | 3.4 | 6.8 | 200.2 | 194 | 90 | 85 | 30 | 75 | 150 | 4 | 0 | 0 | 0 | 15 | 2 | 5 | 4.61 |
| SP | Kershaw, C.Kershaw, Clayton † # | Pigs | L | 121.0 | 28 | 28 | 15 | 9 | 3.53 | .283 | 1.16 | 8.8 | 1.6 | 9.9 | 214.1 | 209 | 88 | 84 | 26 | 39 | 235 | 9 | 0 | 0 | 2 | 17 | 6 | 7 | 3.01 |
| SP | Arrieta, J.Arrieta, Jake † | Huskies | R | 113.0 | 28 | 28 | 14 | 8 | 3.03 | .270 | 1.06 | 6.9 | 2.6 | 8.3 | 187.0 | 144 | 64 | 63 | 21 | 55 | 173 | 4 | 0 | 0 | 1 | 22 | 8 | 6 | 3.62 |
| SP | Schmidt, J.Schmidt, Jason # | Handbasket | R | 103.0 | 27 | 27 | 13 | 7 | 3.58 | .284 | 1.16 | 8.2 | 2.3 | 8.1 | 193.2 | 176 | 79 | 77 | 26 | 49 | 174 | 6 | 0 | 0 | 2 | 17 | 5 | 5 | 3.79 |
| CL | Feliz, N.Feliz, Neftali † | Bombers | R | 99.0 | 46 | 0 | 6 | 2 | 2.81 | .249 | 0.99 | 6.2 | 2.8 | 9.7 | 51.1 | 35 | 16 | 16 | 4 | 16 | 55 | 0 | 24 | 3 | 0 | 0 | 0 | 0 | 2.80 |
| CL | Rivera, M.Rivera, Mariano † | Aces Eights | R | 99.0 | 64 | 0 | 5 | 9 | 4.34 | .289 | 1.18 | 8.9 | 1.8 | 8.5 | 66.1 | 65 | 32 | 32 | 13 | 13 | 62 | 0 | 36 | 7 | 0 | 0 | 3 | 1 | 4.41 |
| CL | Kimbrel, C.Kimbrel, Craig | Handbasket | R | 92.5 | 58 | 0 | 3 | 9 | 3.57 | .256 | 1.02 | 5.9 | 3.3 | 10.3 | 63.0 | 41 | 25 | 25 | 10 | 23 | 72 | 0 | 33 | 3 | 0 | 0 | 1 | 5 | 3.92 |
| SP | Millwood, K.Millwood, Kevin † | Aces Eights | R | 91.0 | 26 | 26 | 14 | 4 | 4.01 | .306 | 1.29 | 8.5 | 3.2 | 6.8 | 168.1 | 158 | 82 | 75 | 24 | 59 | 126 | 1 | 0 | 0 | 0 | 14 | 6 | 2 | 4.52 |