| SP | Martinez, P.Martinez, Pedro † $$ | Mets | R | 105.0 | 17 | 17 | 10 | 6 | 2.62 | .231 | 0.86 | 6.1 | 1.7 | 10.1 | 147.2 | 100 | 43 | 43 | 19 | 27 | 165 | 13 | 0 | 0 | 3 | 13 | 6 | 1 | 3.11 |
| SP | Millwood, K.Millwood, Kevin † | Gladiators | R | 84.0 | 16 | 16 | 12 | 0 | 2.99 | .296 | 1.26 | 7.6 | 3.8 | 6.8 | 87.1 | 73 | 30 | 29 | 10 | 37 | 66 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.25 |
| SP | Halladay, R.Halladay, Roy † | Gladiators | R | 68.0 | 16 | 16 | 10 | 4 | 3.91 | .284 | 1.17 | 8.5 | 2.0 | 6.8 | 106.0 | 100 | 48 | 46 | 16 | 24 | 80 | 6 | 0 | 0 | 2 | 8 | 2 | 0 | 4.19 |
| SP | Greinke, Z.Greinke, Zack # | Snakes | R | 65.0 | 16 | 16 | 8 | 5 | 2.87 | .245 | 0.96 | 7.3 | 1.4 | 9.1 | 113.0 | 92 | 39 | 36 | 12 | 17 | 114 | 0 | 0 | 0 | 0 | 11 | 1 | 2 | 2.84 |
| SP | Duchscherer, J.Duchscherer, Justin # | Red Sox | R | 57.0 | 16 | 16 | 9 | 4 | 3.86 | .289 | 1.19 | 8.6 | 2.1 | 5.9 | 109.2 | 104 | 48 | 47 | 15 | 26 | 71 | 1 | 0 | 0 | 1 | 9 | 4 | 3 | 4.31 |
| SP | Zambrano, C.Zambrano, Carlos # | Gladiators | R | 56.0 | 16 | 16 | 7 | 2 | 3.55 | .272 | 1.09 | 6.5 | 3.3 | 7.7 | 99.0 | 72 | 41 | 39 | 13 | 36 | 85 | 1 | 0 | 0 | 1 | 9 | 3 | 2 | 4.17 |