| SP | Santana, J.Santana, Johan | Twins | L | 214.0 | 35 | 35 | 22 | 7 | 2.31 | .236 | 0.89 | 6.0 | 2.1 | 10.1 | 268.2 | 178 | 70 | 69 | 16 | 62 | 300 | 8 | 0 | 0 | 6 | 29 | 9 | 3 | 2.33 |
| SP | McKnight, T.McKnight, Tony | Colt 45s | R | 199.0 | 36 | 36 | 24 | 8 | 2.97 | .260 | 1.05 | 7.3 | 2.2 | 6.8 | 282.0 | 228 | 94 | 93 | 27 | 68 | 214 | 13 | 0 | 0 | 2 | 28 | 1 | 5 | 3.46 |
| SP | Rodriguez, R.Rodriguez, Ricardo # | Diamondbacks | R | 189.0 | 34 | 34 | 20 | 4 | 2.30 | .245 | 0.96 | 6.1 | 2.5 | 6.6 | 246.1 | 168 | 68 | 63 | 14 | 69 | 181 | 6 | 0 | 0 | 3 | 26 | 3 | 5 | 3.15 |
| CL | Valverde, J.Valverde, Jose | Diamondbacks | R | 173.5 | 71 | 0 | 7 | 5 | 1.25 | .240 | 0.93 | 5.3 | 3.1 | 9.7 | 86.2 | 51 | 12 | 12 | 3 | 30 | 93 | 0 | 43 | 1 | 0 | 0 | 1 | 2 | 2.37 |
| SP | Waechter, D.Waechter, Doug | Rays | R | 156.0 | 33 | 33 | 16 | 9 | 2.31 | .252 | 0.95 | 6.2 | 2.4 | 9.2 | 238.0 | 163 | 63 | 61 | 14 | 64 | 243 | 2 | 0 | 0 | 1 | 27 | 14 | 0 | 2.71 |
| CL | Soriano, R.Soriano, Rafael | Mariners | R | 154.5 | 68 | 0 | 8 | 7 | 2.31 | .247 | 0.96 | 6.5 | 2.2 | 8.8 | 93.2 | 67 | 25 | 24 | 8 | 23 | 91 | 0 | 39 | 3 | 0 | 0 | 2 | 0 | 2.97 |
| CL | Escobar, K.Escobar, Kelvim | Blue Jays | R | 145.0 | 59 | 0 | 9 | 7 | 2.01 | .221 | 0.82 | 5.2 | 2.2 | 9.2 | 89.1 | 51 | 22 | 20 | 8 | 22 | 91 | 0 | 34 | 7 | 0 | 0 | 3 | 3 | 2.97 |