| CL | Kimbrel, C.Kimbrel, Craig † | Angels | R | 200.0 | 78 | 0 | 5 | 4 | 1.09 | .190 | 0.70 | 4.8 | 1.5 | 9.5 | 82.1 | 44 | 10 | 10 | 8 | 14 | 87 | 0 | 58 | 4 | 0 | 0 | 0 | 3 | 2.66 |
| SP | Derringer, P.Derringer, Paul † | Angels | R | 196.0 | 38 | 38 | 26 | 7 | 3.50 | .287 | 1.21 | 8.7 | 2.2 | 4.6 | 288.1 | 279 | 118 | 112 | 28 | 70 | 148 | 15 | 0 | 0 | 5 | 23 | 0 | 3 | 3.97 |
| SP | Parnell, M.Parnell, Mel † | Angels | L | 189.0 | 41 | 41 | 25 | 11 | 3.47 | .282 | 1.16 | 7.5 | 3.0 | 5.2 | 316.2 | 262 | 131 | 122 | 33 | 106 | 183 | 15 | 0 | 0 | 3 | 26 | 5 | 8 | 4.25 |
| CL | Miller, A.Miller, Andrew † | Mariners | L | 166.0 | 70 | 0 | 5 | 3 | 1.88 | .215 | 0.78 | 4.8 | 2.3 | 10.3 | 71.2 | 38 | 15 | 15 | 6 | 18 | 81 | 0 | 48 | 3 | 0 | 0 | 3 | 2 | 2.70 |
| CL | Knebel, C.Knebel, Corey † | Yankees | R | 129.0 | 63 | 0 | 1 | 5 | 2.07 | .260 | 1.06 | 5.4 | 4.2 | 10.1 | 65.1 | 39 | 15 | 15 | 2 | 30 | 73 | 0 | 44 | 3 | 0 | 0 | 0 | 1 | 2.54 |
| SP | Jansen, L.Jansen, Larry † | Mariners | R | 119.0 | 34 | 34 | 20 | 9 | 3.82 | .301 | 1.28 | 9.2 | 2.4 | 4.1 | 221.1 | 225 | 98 | 94 | 24 | 59 | 101 | 1 | 0 | 0 | 0 | 22 | 2 | 3 | 4.33 |
| SP | Humphries, J.Humphries, Johnny # | Angels | R | 111.0 | 28 | 27 | 18 | 7 | 4.14 | .283 | 1.17 | 8.5 | 2.0 | 4.8 | 198.0 | 187 | 92 | 91 | 26 | 44 | 105 | 8 | 0 | 1 | 1 | 15 | 4 | 0 | 4.37 |
| SP | Hutchinson, F.Hutchinson, Fred † | White Sox | R | 109.0 | 33 | 32 | 18 | 11 | 4.14 | .302 | 1.29 | 8.2 | 3.4 | 4.6 | 237.0 | 215 | 110 | 109 | 28 | 90 | 120 | 7 | 0 | 0 | 2 | 15 | 2 | 0 | 4.69 |
| RP | Gallegos, G.Gallegos, Giovanny | Mariners | R | 109.0 | 101 | 0 | 16 | 2 | 3.45 | .281 | 1.17 | 7.4 | 3.2 | 8.6 | 122.2 | 100 | 52 | 47 | 10 | 43 | 117 | 0 | 2 | 1 | 0 | 0 | 1 | 7 | 3.23 |