| SP | Skubal, T.Skubal, Tarik † | Cats | L | 102.0 | 22 | 22 | 14 | 5 | 3.27 | .266 | 1.08 | 7.8 | 2.0 | 11.5 | 145.2 | 126 | 53 | 53 | 12 | 32 | 186 | 0 | 0 | 0 | 0 | 15 | 0 | 4 | 2.17 |
| SP | Pivetta, N.Pivetta, Nick † # | Pigs | R | 102.0 | 22 | 22 | 12 | 8 | 2.30 | .254 | 0.99 | 6.6 | 2.3 | 10.5 | 145.0 | 106 | 39 | 37 | 10 | 37 | 169 | 1 | 0 | 0 | 0 | 18 | 5 | 1 | 2.43 |
| SP | Rogers, T.Rogers, Trevor † $$ | Quakes | L | 95.0 | 22 | 22 | 12 | 6 | 2.95 | .263 | 1.03 | 6.6 | 2.7 | 9.2 | 146.1 | 107 | 54 | 48 | 18 | 44 | 150 | 1 | 0 | 0 | 1 | 16 | 6 | 0 | 3.58 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu $$ | Quakes | R | 88.0 | 21 | 21 | 11 | 4 | 3.09 | .291 | 1.21 | 7.5 | 3.4 | 11.8 | 128.1 | 106 | 45 | 44 | 12 | 49 | 168 | 0 | 0 | 0 | 0 | 12 | 3 | 4 | 2.81 |
| SP | Glasnow, T.Glasnow, Tyler † | Quakes | R | 85.0 | 21 | 21 | 9 | 3 | 2.49 | .243 | 0.92 | 5.2 | 3.1 | 8.9 | 130.0 | 75 | 37 | 36 | 6 | 45 | 129 | 0 | 0 | 0 | 0 | 13 | 5 | 2 | 2.77 |
| SP | Crochet, G.Crochet, Garrett # | Cats | L | 84.0 | 22 | 22 | 13 | 6 | 3.88 | .276 | 1.13 | 8.2 | 1.9 | 11.4 | 139.1 | 127 | 64 | 60 | 19 | 30 | 176 | 0 | 0 | 0 | 0 | 13 | 2 | 1 | 2.94 |
| RP | Svanson, M.Svanson, Matt † | Quakes | R | 84.0 | 63 | 0 | 11 | 2 | 2.60 | .270 | 1.10 | 6.2 | 3.7 | 9.3 | 83.0 | 57 | 25 | 24 | 6 | 34 | 86 | 0 | 4 | 6 | 0 | 0 | 1 | 3 | 3.13 |