| CL | Wagner, B.Wagner, Billy † | Volunteers | L | 109.5 | 51 | 0 | 6 | 3 | 2.79 | .276 | 1.12 | 5.6 | 4.6 | 10.9 | 51.2 | 32 | 18 | 16 | 2 | 26 | 62 | 0 | 29 | 4 | 0 | 0 | 1 | 2 | 2.67 |
| SP | Santana, J.Santana, Johan † # | Serpents | L | 93.0 | 21 | 21 | 12 | 3 | 3.20 | .274 | 1.12 | 7.9 | 2.2 | 7.8 | 143.1 | 125 | 53 | 51 | 13 | 35 | 124 | 1 | 0 | 0 | 0 | 14 | 2 | 5 | 3.22 |
| SP | Scherzer, M.Scherzer, Max † | Dragons | R | 87.0 | 22 | 22 | 10 | 4 | 2.82 | .273 | 1.11 | 6.4 | 3.7 | 8.7 | 143.2 | 101 | 47 | 45 | 11 | 59 | 139 | 0 | 0 | 0 | 0 | 18 | 2 | 1 | 3.34 |
| SP | Kershaw, C.Kershaw, Clayton # | Crabs | L | 86.0 | 22 | 22 | 9 | 8 | 3.19 | .253 | 1.01 | 8.0 | 1.1 | 8.4 | 172.1 | 153 | 64 | 61 | 15 | 21 | 160 | 7 | 0 | 0 | 3 | 13 | 1 | 2 | 2.66 |
| SP | Richard, J.Richard, J.R. $ | Bombers | R | 82.0 | 21 | 21 | 10 | 6 | 3.06 | .254 | 1.01 | 5.0 | 4.1 | 7.3 | 144.0 | 80 | 49 | 49 | 10 | 65 | 116 | 3 | 0 | 0 | 1 | 14 | 2 | 0 | 3.69 |
| RP | Kimbrel, C.Kimbrel, Craig † | Warriors | R | 81.5 | 63 | 0 | 8 | 3 | 2.57 | .252 | 1.00 | 5.3 | 3.7 | 10.9 | 91.0 | 54 | 27 | 26 | 7 | 37 | 110 | 0 | 7 | 3 | 0 | 0 | 1 | 7 | 2.84 |
| SP | deGrom, J.deGrom, Jacob # $$ | Warriors | R | 81.0 | 22 | 22 | 10 | 6 | 3.19 | .254 | 1.01 | 6.7 | 2.4 | 9.2 | 144.0 | 107 | 52 | 51 | 17 | 39 | 147 | 1 | 0 | 0 | 1 | 17 | 1 | 0 | 3.33 |
| SP | Martinez, P.Martinez, Pedro † | BLACKANDREDS | R | 78.0 | 22 | 22 | 8 | 5 | 3.02 | .290 | 1.21 | 7.8 | 3.1 | 8.2 | 158.0 | 137 | 54 | 53 | 12 | 54 | 144 | 2 | 0 | 0 | 0 | 16 | 3 | 1 | 3.25 |