| SP | Kershaw, C.Kershaw, Clayton | Twins | L | 54.0 | 9 | 9 | 6 | 1 | 2.20 | .267 | 1.08 | 7.3 | 2.5 | 8.6 | 69.2 | 56 | 22 | 17 | 5 | 19 | 66 | 0 | 0 | 0 | 0 | 7 | 1 | 4 | 2.90 |
| SP | Koufax, S.Koufax, Sandy # | Twins | L | 48.0 | 9 | 9 | 6 | 3 | 3.06 | .243 | 0.95 | 7.3 | 1.3 | 8.2 | 70.2 | 57 | 24 | 24 | 8 | 10 | 64 | 4 | 0 | 0 | 1 | 6 | 1 | 2 | 3.13 |
| SP | Gonsolin, T.Gonsolin, Tony | Twins | R | 42.0 | 9 | 9 | 5 | 1 | 2.28 | .275 | 1.14 | 7.0 | 3.3 | 6.2 | 55.1 | 43 | 16 | 14 | 3 | 20 | 38 | 0 | 0 | 0 | 0 | 5 | 0 | 3 | 3.42 |
| SP | Verlander, J.Verlander, Justin | Colt .45s | R | 41.0 | 9 | 9 | 6 | 2 | 3.36 | .300 | 1.24 | 7.3 | 3.8 | 10.1 | 59.0 | 48 | 22 | 22 | 6 | 25 | 66 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 3.51 |
| SP | Scherzer, M.Scherzer, Max | Legends | R | 40.0 | 9 | 9 | 5 | 3 | 2.53 | .286 | 1.19 | 8.3 | 2.4 | 7.9 | 64.0 | 59 | 21 | 18 | 3 | 17 | 56 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 2.70 |
| RP | Frieri, E.Frieri, Ernesto | Angels | R | 37.0 | 21 | 0 | 5 | 0 | 4.56 | .300 | 1.29 | 7.6 | 4.3 | 9.0 | 25.2 | 21 | 13 | 13 | 1 | 12 | 25 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2.96 |
| SP | Woodruff, B.Woodruff, Brandon | Brewers | R | 35.0 | 9 | 8 | 6 | 2 | 3.99 | .310 | 1.35 | 9.0 | 3.3 | 9.4 | 49.2 | 49 | 22 | 22 | 6 | 18 | 51 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 3.61 |