| SP | Kershaw, C.Kershaw, Clayton | Twins | L | 71.0 | 13 | 13 | 8 | 3 | 2.45 | .272 | 1.10 | 7.9 | 2.1 | 8.7 | 102.2 | 89 | 35 | 28 | 8 | 24 | 99 | 1 | 0 | 0 | 0 | 10 | 2 | 5 | 2.84 |
| SP | Koufax, S.Koufax, Sandy # | Twins | L | 69.0 | 14 | 14 | 9 | 4 | 3.54 | .258 | 1.01 | 7.5 | 1.7 | 8.8 | 106.2 | 88 | 42 | 42 | 13 | 20 | 104 | 6 | 0 | 0 | 2 | 9 | 3 | 2 | 3.28 |
| SP | Verlander, J.Verlander, Justin | Colt .45s | R | 66.0 | 13 | 13 | 9 | 2 | 3.07 | .292 | 1.20 | 7.2 | 3.7 | 9.3 | 88.0 | 70 | 30 | 30 | 8 | 36 | 91 | 0 | 0 | 0 | 0 | 9 | 3 | 2 | 3.44 |
| SP | Driscoll, D.Driscoll, Denny # | Cubs | L | 57.0 | 14 | 14 | 7 | 3 | 3.35 | .303 | 1.28 | 9.9 | 1.7 | 5.3 | 96.2 | 106 | 40 | 36 | 8 | 18 | 56 | 6 | 0 | 0 | 1 | 9 | 2 | 0 | 3.54 |
| SP | Gonsolin, T.Gonsolin, Tony | Twins | R | 50.0 | 13 | 13 | 7 | 3 | 2.95 | .281 | 1.17 | 7.9 | 2.7 | 6.5 | 79.1 | 69 | 30 | 26 | 5 | 24 | 57 | 0 | 0 | 0 | 0 | 7 | 0 | 3 | 3.29 |