| SP | Kershaw, C.Kershaw, Clayton † # | Bulldogs | L | 131.0 | 28 | 28 | 16 | 5 | 3.40 | .266 | 1.05 | 8.1 | 1.4 | 9.9 | 214.2 | 192 | 81 | 81 | 26 | 34 | 235 | 4 | 0 | 0 | 1 | 17 | 7 | 4 | 2.96 |
| SP | Fernandez, S.Fernandez, Sid † | Charlie Browns | L | 109.0 | 26 | 26 | 14 | 8 | 3.07 | .274 | 1.11 | 5.9 | 4.1 | 8.1 | 179.0 | 117 | 62 | 61 | 15 | 81 | 162 | 2 | 0 | 0 | 2 | 17 | 5 | 0 | 3.72 |
| SP | Scherzer, M.Scherzer, Max † | Nightmares | R | 103.0 | 28 | 28 | 14 | 9 | 3.49 | .286 | 1.18 | 7.0 | 3.6 | 9.8 | 193.1 | 151 | 75 | 75 | 24 | 77 | 211 | 2 | 0 | 0 | 0 | 17 | 4 | 4 | 3.69 |
| SP | deGrom, J.deGrom, Jacob † $ | Fighting Orange | R | 103.0 | 28 | 28 | 12 | 8 | 2.99 | .260 | 1.03 | 6.8 | 2.5 | 9.4 | 192.1 | 145 | 65 | 64 | 23 | 54 | 200 | 1 | 0 | 0 | 0 | 23 | 4 | 0 | 3.38 |
| SP | Fernandez, J.Fernandez, Jose # | Red Sox | R | 102.0 | 27 | 27 | 14 | 7 | 3.27 | .266 | 1.06 | 6.3 | 3.3 | 8.9 | 165.1 | 116 | 63 | 60 | 17 | 60 | 163 | 1 | 0 | 0 | 1 | 19 | 4 | 2 | 3.53 |
| SP | Carlton, S.Carlton, Steve † # | Charlie Browns | L | 93.0 | 26 | 26 | 12 | 10 | 3.46 | .272 | 1.09 | 6.8 | 3.0 | 6.5 | 197.2 | 149 | 80 | 76 | 26 | 66 | 142 | 8 | 0 | 0 | 1 | 16 | 7 | 4 | 4.39 |
| SP | Arrieta, J.Arrieta, Jake # | Serpents | R | 87.0 | 28 | 28 | 12 | 9 | 3.65 | .290 | 1.20 | 7.8 | 3.0 | 8.9 | 195.0 | 169 | 81 | 79 | 22 | 65 | 193 | 0 | 0 | 0 | 0 | 18 | 5 | 3 | 3.56 |
| CL | Hoffman, T.Hoffman, Trevor | COWBOYS | R | 87.0 | 53 | 0 | 2 | 3 | 2.65 | .269 | 1.09 | 5.5 | 4.3 | 8.8 | 54.1 | 33 | 16 | 16 | 4 | 26 | 53 | 0 | 28 | 5 | 0 | 0 | 1 | 2 | 3.50 |