| SP | Peralta, F.Peralta, Freddy † | Locos | R | 101.0 | 24 | 24 | 12 | 3 | 2.84 | .271 | 1.07 | 7.0 | 2.7 | 9.6 | 142.2 | 110 | 47 | 45 | 20 | 43 | 152 | 1 | 0 | 0 | 1 | 12 | 6 | 3 | 3.73 |
| SP | Greene, H.Greene, Hunter † | North Stars | R | 97.0 | 25 | 25 | 13 | 6 | 3.08 | .295 | 1.23 | 7.6 | 3.6 | 9.7 | 149.0 | 125 | 51 | 51 | 14 | 59 | 161 | 0 | 0 | 0 | 0 | 15 | 3 | 2 | 3.31 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu $$ | Chuggers | R | 90.0 | 25 | 25 | 13 | 7 | 3.48 | .315 | 1.36 | 7.9 | 4.4 | 11.4 | 144.2 | 126 | 62 | 56 | 18 | 71 | 183 | 0 | 0 | 0 | 0 | 12 | 3 | 4 | 3.63 |
| SP | Luzardo, J.Luzardo, Jesus † | Suns | L | 88.0 | 24 | 24 | 13 | 9 | 3.37 | .298 | 1.24 | 7.9 | 3.3 | 10.4 | 149.2 | 130 | 56 | 56 | 17 | 55 | 172 | 1 | 0 | 0 | 0 | 16 | 6 | 2 | 3.40 |
| SP | Skubal, T.Skubal, Tarik $$ | Locos | L | 87.0 | 25 | 25 | 12 | 5 | 3.81 | .287 | 1.19 | 8.3 | 2.4 | 10.7 | 163.0 | 150 | 74 | 69 | 15 | 44 | 194 | 0 | 0 | 0 | 0 | 15 | 3 | 1 | 2.68 |
| SP | Cameron, N.Cameron, Noah † | PATRIOTS | L | 83.0 | 24 | 24 | 12 | 5 | 3.60 | .297 | 1.23 | 7.7 | 3.4 | 8.8 | 147.1 | 126 | 66 | 59 | 11 | 55 | 143 | 0 | 0 | 0 | 0 | 11 | 6 | 6 | 3.27 |
| SP | Pivetta, N.Pivetta, Nick # | Demons | R | 82.0 | 25 | 25 | 10 | 4 | 3.49 | .281 | 1.14 | 8.1 | 2.3 | 10.7 | 152.1 | 136 | 60 | 59 | 17 | 38 | 181 | 0 | 0 | 0 | 0 | 15 | 5 | 0 | 2.92 |