| SP | Hernandez, F.Hernandez, Felix † # | Mustangs | R | 114.0 | 23 | 23 | 14 | 7 | 3.13 | .261 | 1.06 | 7.4 | 2.1 | 9.5 | 178.0 | 147 | 66 | 62 | 27 | 41 | 188 | 5 | 0 | 0 | 2 | 17 | 1 | 6 | 3.57 |
| SP | deGrom, J.deGrom, Jacob † # | Tigers | R | 102.0 | 24 | 24 | 12 | 6 | 3.07 | .277 | 1.13 | 8.0 | 2.1 | 10.0 | 170.0 | 152 | 60 | 58 | 15 | 40 | 188 | 2 | 0 | 0 | 1 | 17 | 3 | 2 | 2.69 |
| SP | Hudson, D.Hudson, Daniel † | Boys | R | 80.0 | 22 | 22 | 14 | 7 | 4.14 | .311 | 1.32 | 8.3 | 3.6 | 7.4 | 141.1 | 130 | 69 | 65 | 19 | 57 | 116 | 2 | 0 | 0 | 0 | 15 | 4 | 5 | 4.40 |
| RP | Betances, D.Betances, Dellin † | Reapers | R | 79.5 | 66 | 0 | 9 | 2 | 3.50 | .290 | 1.19 | 7.4 | 3.3 | 11.2 | 87.1 | 72 | 38 | 34 | 9 | 32 | 108 | 0 | 7 | 2 | 0 | 0 | 3 | 2 | 3.07 |
| CL | Chapman, A.Chapman, Aroldis † | Grays | L | 75.0 | 59 | 0 | 5 | 6 | 4.03 | .335 | 1.48 | 7.4 | 6.0 | 11.1 | 60.1 | 49 | 27 | 27 | 6 | 40 | 74 | 0 | 22 | 5 | 0 | 0 | 2 | 2 | 3.93 |
| SP | Kershaw, C.Kershaw, Clayton | Mustangs | L | 74.0 | 24 | 24 | 9 | 7 | 3.93 | .294 | 1.24 | 9.3 | 1.8 | 10.5 | 181.0 | 187 | 80 | 79 | 25 | 37 | 211 | 4 | 0 | 0 | 1 | 12 | 2 | 5 | 3.11 |