| SP | Marichal, J.Marichal, Juan † | 65-04-09 SFG | R | 148.0 | 36 | 36 | 17 | 8 | 3.40 | .268 | 1.08 | 7.7 | 2.1 | 6.9 | 254.0 | 216 | 98 | 96 | 31 | 59 | 195 | 13 | 0 | 0 | 5 | 20 | 4 | 1 | 3.80 |
| SP | Miller, B.Miller, Bryce † | Mariners | R | 123.0 | 33 | 33 | 17 | 5 | 3.35 | .280 | 1.13 | 7.6 | 2.6 | 7.5 | 193.1 | 163 | 75 | 72 | 22 | 56 | 160 | 0 | 0 | 0 | 0 | 23 | 7 | 2 | 3.80 |
| SP | Gilbert, L.Gilbert, Logan | Mariners | R | 116.0 | 35 | 35 | 16 | 5 | 3.65 | .300 | 1.27 | 9.0 | 2.5 | 7.9 | 212.0 | 212 | 87 | 86 | 25 | 58 | 185 | 0 | 0 | 0 | 0 | 25 | 2 | 14 | 3.64 |
| CL | Rivera, M.Rivera, Mariano † | LEMMINGS | R | 113.0 | 53 | 0 | 2 | 3 | 3.43 | .272 | 1.12 | 7.8 | 2.5 | 9.2 | 44.2 | 38 | 18 | 17 | 4 | 12 | 45 | 0 | 42 | 6 | 0 | 0 | 0 | 0 | 2.95 |
| SP | Santana, J.Santana, Johan | Twins | L | 108.0 | 36 | 36 | 15 | 8 | 4.21 | .304 | 1.27 | 9.0 | 2.4 | 8.4 | 254.2 | 255 | 120 | 119 | 29 | 68 | 236 | 5 | 0 | 0 | 3 | 17 | 11 | 1 | 3.56 |
| CL | Miller, T.Miller, Tyson † | Mariners | R | 107.5 | 74 | 0 | 4 | 10 | 3.48 | .267 | 1.07 | 6.5 | 3.1 | 6.6 | 75.0 | 54 | 33 | 29 | 6 | 26 | 55 | 0 | 39 | 6 | 0 | 0 | 2 | 0 | 3.69 |