| SP | Greinke, Z.Greinke, Zack † | Mustangs | R | 147.0 | 27 | 27 | 16 | 3 | 2.59 | .268 | 1.08 | 7.2 | 2.6 | 6.9 | 201.2 | 160 | 60 | 58 | 13 | 58 | 154 | 5 | 0 | 0 | 3 | 21 | 4 | 2 | 3.23 |
| SP | Maddux, G.Maddux, Greg † $$ | Mustangs | R | 116.0 | 28 | 28 | 16 | 7 | 3.54 | .288 | 1.19 | 8.6 | 2.2 | 5.9 | 203.2 | 193 | 83 | 80 | 18 | 49 | 132 | 5 | 0 | 0 | 2 | 16 | 5 | 6 | 3.65 |
| SP | Martinez, P.Martinez, Pedro | Nightmares | R | 115.0 | 28 | 28 | 14 | 5 | 3.55 | .265 | 1.07 | 7.3 | 2.4 | 9.8 | 202.2 | 163 | 81 | 80 | 21 | 53 | 220 | 4 | 0 | 0 | 1 | 20 | 3 | 3 | 3.00 |
| SP | Arrieta, J.Arrieta, Jake † $ | Middlemen | R | 111.0 | 27 | 27 | 14 | 8 | 3.35 | .286 | 1.19 | 7.9 | 2.9 | 8.7 | 204.1 | 178 | 81 | 76 | 22 | 65 | 197 | 3 | 0 | 0 | 1 | 15 | 2 | 1 | 3.46 |
| SP | deGrom, J.deGrom, Jacob $ | Middlemen | R | 110.0 | 26 | 26 | 13 | 5 | 3.03 | .273 | 1.11 | 7.7 | 2.3 | 10.0 | 175.0 | 150 | 67 | 59 | 18 | 44 | 195 | 1 | 0 | 0 | 0 | 17 | 3 | 0 | 2.91 |
| SP | Hunter, C.Hunter, Catfish # | Suns | R | 109.0 | 27 | 27 | 13 | 10 | 3.35 | .270 | 1.09 | 7.7 | 2.1 | 6.0 | 215.0 | 185 | 86 | 80 | 25 | 50 | 144 | 10 | 0 | 0 | 3 | 16 | 3 | 3 | 3.91 |
| SP | Kershaw, C.Kershaw, Clayton # | Reapers | L | 96.0 | 28 | 28 | 11 | 11 | 3.35 | .284 | 1.16 | 8.6 | 1.9 | 9.0 | 212.1 | 203 | 82 | 79 | 29 | 44 | 211 | 7 | 0 | 0 | 1 | 19 | 6 | 8 | 3.50 |