| SP | Greinke, Z.Greinke, Zack † | Mustangs | R | 138.0 | 25 | 25 | 15 | 3 | 2.61 | .267 | 1.07 | 7.2 | 2.5 | 7.0 | 186.1 | 148 | 56 | 54 | 11 | 52 | 144 | 5 | 0 | 0 | 3 | 20 | 4 | 2 | 3.12 |
| SP | Maddux, G.Maddux, Greg † $$ | Mustangs | R | 123.0 | 26 | 26 | 16 | 6 | 3.19 | .277 | 1.13 | 8.2 | 1.9 | 5.9 | 194.2 | 177 | 72 | 69 | 15 | 42 | 127 | 5 | 0 | 0 | 2 | 16 | 5 | 5 | 3.42 |
| SP | Arrieta, J.Arrieta, Jake † $ | Middlemen | R | 115.0 | 25 | 25 | 14 | 6 | 3.16 | .282 | 1.17 | 7.7 | 2.8 | 8.7 | 190.2 | 163 | 72 | 67 | 19 | 60 | 183 | 3 | 0 | 0 | 1 | 15 | 2 | 1 | 3.35 |
| SP | Martinez, P.Martinez, Pedro | Nightmares | R | 110.0 | 26 | 26 | 13 | 4 | 3.52 | .263 | 1.06 | 7.2 | 2.3 | 9.8 | 189.1 | 152 | 75 | 74 | 21 | 48 | 205 | 4 | 0 | 0 | 1 | 19 | 3 | 3 | 3.08 |
| SP | Hunter, C.Hunter, Catfish # | Suns | R | 106.0 | 25 | 25 | 12 | 9 | 3.18 | .260 | 1.04 | 7.4 | 1.9 | 6.3 | 200.2 | 165 | 75 | 71 | 23 | 43 | 140 | 10 | 0 | 0 | 3 | 16 | 3 | 3 | 3.79 |
| SP | deGrom, J.deGrom, Jacob $ | Middlemen | R | 104.0 | 24 | 24 | 12 | 5 | 2.88 | .271 | 1.10 | 7.7 | 2.3 | 10.0 | 162.1 | 138 | 60 | 52 | 14 | 41 | 180 | 1 | 0 | 0 | 0 | 16 | 2 | 0 | 2.70 |