| SP | Arrieta, J.Arrieta, Jake † | Lincoln Giants | R | 119.0 | 29 | 29 | 15 | 5 | 2.92 | .263 | 1.06 | 6.8 | 2.7 | 7.1 | 185.0 | 140 | 62 | 60 | 12 | 56 | 145 | 0 | 0 | 0 | 0 | 19 | 2 | 9 | 3.22 |
| CL | Betances, D.Betances, Dellin # | Ducks | R | 104.5 | 50 | 0 | 7 | 6 | 3.21 | .304 | 1.31 | 8.5 | 3.4 | 9.0 | 53.1 | 50 | 20 | 19 | 8 | 20 | 53 | 0 | 29 | 5 | 0 | 0 | 0 | 2 | 4.09 |
| SP | Drysdale, D.Drysdale, Don # | Devils | R | 104.0 | 28 | 28 | 14 | 7 | 3.82 | .295 | 1.23 | 8.5 | 2.7 | 4.8 | 214.2 | 201 | 101 | 91 | 19 | 64 | 114 | 10 | 0 | 0 | 2 | 16 | 4 | 3 | 4.04 |
| SP | Koufax, S.Koufax, Sandy # | Tigers | L | 96.0 | 29 | 29 | 12 | 13 | 3.67 | .294 | 1.22 | 8.2 | 2.8 | 8.3 | 223.1 | 203 | 97 | 91 | 18 | 70 | 206 | 11 | 0 | 0 | 2 | 17 | 6 | 2 | 3.22 |
| SP | Greinke, Z.Greinke, Zack # | Highlanders | R | 94.0 | 28 | 28 | 14 | 10 | 3.77 | .267 | 1.09 | 7.4 | 2.4 | 6.3 | 207.2 | 170 | 92 | 87 | 20 | 56 | 146 | 4 | 0 | 0 | 0 | 18 | 1 | 3 | 3.67 |