| SP | Arrieta, J.Arrieta, Jake † | Lincoln Giants | R | 137.0 | 35 | 35 | 18 | 7 | 3.00 | .258 | 1.03 | 6.8 | 2.6 | 6.8 | 218.2 | 164 | 75 | 73 | 14 | 62 | 165 | 0 | 0 | 0 | 0 | 22 | 2 | 10 | 3.20 |
| CL | Chapman, A.Chapman, Aroldis † | Classics | L | 130.0 | 59 | 0 | 2 | 3 | 2.64 | .253 | 1.02 | 6.1 | 3.1 | 9.5 | 58.0 | 39 | 20 | 17 | 5 | 20 | 61 | 0 | 44 | 4 | 0 | 0 | 0 | 3 | 3.05 |
| CL | Rivera, M.Rivera, Mariano | Sluggers | R | 119.0 | 62 | 0 | 8 | 5 | 3.64 | .301 | 1.26 | 9.3 | 2.1 | 9.4 | 64.1 | 66 | 27 | 26 | 10 | 15 | 67 | 0 | 32 | 5 | 0 | 0 | 2 | 1 | 3.73 |
| CL | Betances, D.Betances, Dellin # | Ducks | R | 117.0 | 56 | 0 | 7 | 7 | 3.03 | .307 | 1.33 | 8.5 | 3.5 | 8.5 | 59.1 | 56 | 22 | 20 | 8 | 23 | 56 | 0 | 34 | 5 | 0 | 0 | 0 | 3 | 4.03 |
| SP | Leonard, D.Leonard, Dutch | Lincoln Giants | L | 115.0 | 33 | 33 | 15 | 12 | 2.85 | .270 | 1.10 | 6.7 | 3.2 | 4.7 | 217.2 | 162 | 73 | 69 | 8 | 78 | 113 | 2 | 0 | 0 | 2 | 25 | 1 | 1 | 3.53 |
| SP | Fernandez, S.Fernandez, Sid † $ | Highlanders | L | 113.0 | 31 | 31 | 17 | 9 | 3.77 | .304 | 1.29 | 7.6 | 3.9 | 8.5 | 203.0 | 172 | 89 | 85 | 24 | 89 | 192 | 2 | 0 | 0 | 1 | 18 | 5 | 2 | 4.03 |