| SP | Strasburg, S.Strasburg, Stephen † # | Devils | R | 156.0 | 36 | 36 | 22 | 9 | 3.55 | .268 | 1.08 | 7.4 | 2.4 | 10.6 | 248.1 | 204 | 101 | 98 | 32 | 65 | 293 | 1 | 0 | 0 | 0 | 25 | 4 | 7 | 3.15 |
| SP | Glasnow, T.Glasnow, Tyler # | Red Bears | R | 116.0 | 38 | 38 | 18 | 11 | 3.75 | .285 | 1.15 | 7.9 | 2.4 | 10.9 | 208.2 | 183 | 90 | 87 | 26 | 56 | 251 | 0 | 0 | 0 | 0 | 13 | 11 | 3 | 3.18 |
| SP | Verlander, J.Verlander, Justin † | Mascots | R | 115.0 | 38 | 38 | 17 | 12 | 4.19 | .288 | 1.19 | 8.2 | 2.5 | 10.9 | 253.1 | 230 | 118 | 118 | 30 | 71 | 306 | 6 | 0 | 0 | 1 | 22 | 7 | 4 | 3.05 |
| CL | Clippard, T.Clippard, Tyler | Planes | R | 109.0 | 68 | 0 | 3 | 7 | 3.28 | .287 | 1.19 | 7.3 | 3.6 | 10.3 | 68.2 | 55 | 28 | 25 | 7 | 27 | 78 | 0 | 38 | 5 | 0 | 0 | 1 | 4 | 3.28 |
| SP | Clevinger, M.Clevinger, Mike # | Mustangs | R | 103.0 | 38 | 38 | 16 | 10 | 4.27 | .315 | 1.36 | 9.0 | 3.3 | 11.1 | 232.0 | 231 | 117 | 110 | 35 | 84 | 285 | 1 | 0 | 0 | 1 | 19 | 5 | 0 | 3.66 |
| SP | Castillo, L.Castillo, Luis † | Spiders | R | 103.0 | 33 | 33 | 10 | 3 | 3.33 | .307 | 1.27 | 7.1 | 4.4 | 11.9 | 205.1 | 161 | 77 | 76 | 22 | 100 | 271 | 0 | 0 | 0 | 0 | 15 | 12 | 7 | 3.39 |
| RP | Osuna, R.Osuna, Roberto † | Mascots | R | 102.5 | 91 | 0 | 7 | 2 | 3.02 | .273 | 1.09 | 7.8 | 2.0 | 10.1 | 125.0 | 108 | 42 | 42 | 18 | 28 | 140 | 0 | 15 | 4 | 0 | 0 | 5 | 2 | 3.42 |